| English Dictionary |
CONJUGATE
| Pronunciation (US): |  | (GB): | |
| IPA (US): |  |
Dictionary entry overview: What does conjugate mean?
• CONJUGATE (noun)
The noun CONJUGATE has 1 sense:
1. a mixture of two partially miscible liquids A and B produces two conjugate solutions: one of A in B and another of B in A
Familiarity information: CONJUGATE used as a noun is very rare.
• CONJUGATE (adjective)
The adjective CONJUGATE has 4 senses:
1. joined together especially in a pair or pairs
2. (of a pinnate leaflet) having only one pair of leaflets
3. formed by the union of two compounds
4. of an organic compound; containing two or more double bonds each separated from the other by a single bond
Familiarity information: CONJUGATE used as an adjective is uncommon.
• CONJUGATE (verb)
The verb CONJUGATE has 3 senses:
1. unite chemically so that the product is easily broken down into the original compounds
2. add inflections showing person, number, gender, tense, aspect, etc.
3. undergo conjugation
Familiarity information: CONJUGATE used as a verb is uncommon.
Dictionary entry details
Sense 1
Meaning:
A mixture of two partially miscible liquids A and B produces two conjugate solutions: one of A in B and another of B in A
Classified under:
Nouns denoting substances
Synonyms:
conjugate; conjugate solution
Hypernyms ("conjugate" is a kind of...):
solution (a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution)
Derivation:
conjugate (unite chemically so that the product is easily broken down into the original compounds)
Sense 1
Meaning:
Joined together especially in a pair or pairs
Synonyms:
conjugate; conjugated; coupled
Similar:
united (characterized by unity; being or joined into a single entity)
Sense 2
Meaning:
(of a pinnate leaflet) having only one pair of leaflets
Similar:
compound (composed of more than one part)
Sense 3
Meaning:
Formed by the union of two compounds
Synonyms:
conjugate; conjugated
Context example:
a conjugated protein
Similar:
bound (held with another element, substance or material in chemical or physical union)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Sense 4
Meaning:
Of an organic compound; containing two or more double bonds each separated from the other by a single bond
Synonyms:
conjugate; conjugated
Similar:
bound (held with another element, substance or material in chemical or physical union)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
| Conjugation: |
... he / she / it conjugates Past simple: conjugated
Past participle: conjugated
-ing form: conjugating
Sense 1
Meaning:
Unite chemically so that the product is easily broken down into the original compounds
Classified under:
Verbs of size, temperature change, intensifying, etc.
Hypernyms (to "conjugate" is one way to...):
blend; coalesce; combine; commingle; conflate; flux; fuse; immix; meld; merge; mix (mix together different elements)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Sentence frame:
Somebody ----s something
Derivation:
conjugate (a mixture of two partially miscible liquids A and B produces two conjugate solutions: one of A in B and another of B in A)
Sense 2
Meaning:
Add inflections showing person, number, gender, tense, aspect, etc.
Classified under:
Verbs of telling, asking, ordering, singing
Context example:
conjugate the verb
Hypernyms (to "conjugate" is one way to...):
inflect (change the form of a word in accordance as required by the grammatical rules of the language)
Sentence frame:
Somebody ----s something
Derivation:
conjugation (a class of verbs having the same inflectional forms)
conjugation (the complete set of inflected forms of a verb)
conjugation (the inflection of verbs)
Sense 3
Meaning:
Undergo conjugation
Classified under:
Verbs of size, temperature change, intensifying, etc.
Hypernyms (to "conjugate" is one way to...):
change (undergo a change; become different in essence; losing one's or its original nature)
Domain category:
biological science; biology (the science that studies living organisms)
Sentence frame:
Something ----s
Derivation:
conjugation (the act of pairing a male and female for reproductive purposes)
Context examples
This agent can also be conjugated to toxins for potential use in cancer immunotherapy.
(Monoclonal Antibody 3A1, NCI Thesaurus)
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows the antibody to be labeled with a metal species.
(MoAb Bombesin (ITC-D), NCI Thesaurus)
Conjugated MoAb 81C6 may be used in diagnosis or treatment of cancers that over-express tenascin.
(Monoclonal Antibody 81C6, NCI Thesaurus)
Monoclonal antibody B3 can be conjugated with various toxins in order to target their cytotoxic activity to tumor cells expressing these carbohydrate antigens.
(Monoclonal Antibody B3, NCI Thesaurus)
MOAB IMMU-14 can be conjugated with a radioactive element for use in radioimmunotherapy (RIT), a regimen that uses a tumor-specific monoclonal antibody to deliver targeted radiation to cancer cells.
(Monoclonal Antibody IMMU-14, NCI Thesaurus)
A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A DTPA).
(MOAB B-3-CHX-A-DTPA, NCI Thesaurus)
It belongs to the family of drugs called antibody drug conjugates.
(MLN2704, NCI Dictionary)
Linkage of the antibody and drug, through a nonreducible linker, appears to contribute to the improved efficacy and reduced toxicity of this antibody-drug conjugate (ADC) compared to similar ADCs constructed with reducible linkers.
(Anti-EGFR TAP Antibody-drug Conjugate IMGN289, NCI Thesaurus)
A water-soluble, positively charged fusion protein consisting of a luteinizing hormone releasing hormone (LHRH) receptor-targeting ligand conjugated to the membrane-disrupting peptide CLIP 71 with membrane-disrupting and potential antineoplastic activities.
(Membrane-Disrupting Peptide EP-100, NCI Thesaurus)
A conjugate vaccine of meningococcal polysaccharide used for active immunization against invasive meningococcal disease caused by Neisseria meningiditis serogroups A, C, Y, and W-135.
(Meningococcal Conjugate Vaccine MCV4, NCI Thesaurus)
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