THALIDOMIDE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does thalidomide mean? 

• THALIDOMIDE (noun)
  The noun THALIDOMIDE has 1 sense:

1. a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis

  Familiarity information: THALIDOMIDE used as a noun is very rare.

 Dictionary entry details 

• THALIDOMIDE (noun)

Sense 1

Meaning:

A sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis

Classified under:

Nouns denoting man-made objects

Hypernyms ("thalidomide" is a kind of...):

sedative-hypnotic; sedative-hypnotic drug (a sedative that depresses activity of the central nervous system and reduces anxiety and induces sleep)

teratogen (any agent that interferes with normal embryonic development: alcohol or thalidomide or X-rays or rubella are examples)

 Context examples 

It is similar but not identical to thalidomide.

(CC-1088, NCI Dictionary)

A thalidomide analog with potential antineoplastic activity.

(Lenalidomide, NCI Thesaurus)

A drug that is a form of thalidomide, and is used to treat multiple myeloma that has not gotten better with other anticancer drugs.

(CC-4047, NCI Dictionary)

A proprietary, orally available, small molecule and thalidomide analog, with potential immunomodulating and antineoplastic activity.

(Immunomodulatory Agent CC-11006, NCI Thesaurus)

An analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs).

(CC-1088, NCI Thesaurus)

A chemotherapy combination used in the treatment of cancers such as multiple myeloma and consisting of dexamethasone (antiinflammatory), cisplatin, Dexamethasone, cyclophosphamide, etoposide (cytostatic) and thalidomide (antiangiogenic).

(Cisplatin/Cyclophosphamide/Dexamethasone/Etoposide/Thalidomide, NCI Thesaurus)

A regimen consisting of dexamethasone, thalidomide (DT) and cisplatin, doxorubicin, cyclophosphamide and etoposide (PACE) used for the treatment of relapsed and refractory multiple myeloma.

(DT-PACE Regimen, NCI Thesaurus)

A drug that is similar to thalidomide, and is used to treat multiple myeloma and certain types of anemia.

(CC-5013, NCI Dictionary)

A regimen consisting of melphalan, prednisone and thalidomide used as induction therapy for multiple myeloma.

(MPT Regimen, NCI Thesaurus)

CC-11006 appears to have a similar mechanism to thalidomide and may modulate the expression of proinflammatory and regulatory cytokines.

(Immunomodulatory Agent CC-11006, NCI Thesaurus)