SEVERELY

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 Dictionary entry overview: What does severely mean? 

• SEVERELY (adverb)
  The adverb SEVERELY has 3 senses:

1. to a severe or serious degree

2. with sternness; in a severe manner

3. causing great damage or hardship

  Familiarity information: SEVERELY used as an adverb is uncommon.

 Dictionary entry details 

• SEVERELY (adverb)

Sense 1

Meaning:

To a severe or serious degree

Synonyms:

badly; gravely; seriously; severely

Context example:

was seriously ill

Pertainym:

severe (intensely or extremely bad or unpleasant in degree or quality)

Sense 2

Meaning:

With sternness; in a severe manner

Synonyms:

severely; sternly

Context example:

peered severely over her glasses

Pertainym:

severe (unsparing and uncompromising in discipline or judgment)

Sense 3

Meaning:

Causing great damage or hardship

Synonyms:

hard; severely

Context example:

she was severely affected by the bank's failure

Pertainym:

severe (very bad in degree or extent)

 Context examples 

This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C9*6 protein.

(CYP2C9*6 Allele, NCI Thesaurus)

“I must really ask you to be a little more quiet!” said Holmes severely.

(The Adventures of Sherlock Holmes, by Sir Arthur Conan Doyle)

Terminology used to describe the part of the graft that is most severely stenotic.

(CDISC SDTM Location of Most Severe Stenosis Within a Graft Terminology, NCI Thesaurus/CDISC)

This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 3A4*17 protein.

(CYP3A4*17 Allele, NCI Thesaurus)

This process severely interferes with movement in the joint.

(Destructive Arthritis, NCI Thesaurus)

This alteration severely decreases the enzymatic activity of the cytochrome P450 3A5*3 protein.

(CYP3A5*3 Allele, NCI Thesaurus)

I felt for my sister most severely.

(Sense and Sensibility, by Jane Austen)

This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C9*11 protein.

(CYP2C9*11 Allele, NCI Thesaurus)

This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C19*10 protein.

(CYP2C19*10 Allele, NCI Thesaurus)

This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 1A2*11 protein.

(CYP1A2*11 Allele, NCI Thesaurus)