REGRESSION

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 Dictionary entry overview: What does regression mean? 

• REGRESSION (noun)
  The noun REGRESSION has 4 senses:

1. an abnormal state in which development has stopped prematurely

2. (psychiatry) a defense mechanism in which you flee from reality by assuming a more infantile state

3. the relation between selected values of x and observed values of y (from which the most probable value of y can be predicted for any value of x)

4. returning to a former state

  Familiarity information: REGRESSION used as a noun is uncommon.

 Dictionary entry details 

• REGRESSION (noun)

Sense 1

Meaning:

An abnormal state in which development has stopped prematurely

Classified under:

Nouns denoting stable states of affairs

Synonyms:

arrested development; fixation; infantile fixation; regression

Hypernyms ("regression" is a kind of...):

abnormalcy; abnormality (an abnormal physical condition resulting from defective genes or developmental deficiencies)

Sense 2

Meaning:

(psychiatry) a defense mechanism in which you flee from reality by assuming a more infantile state

Classified under:

Nouns denoting natural processes

Hypernyms ("regression" is a kind of...):

defence; defence mechanism; defence reaction; defense; defense mechanism; defense reaction ((psychiatry) an unconscious process that tries to reduce the anxiety associated with instinctive desires)

Domain category:

psychiatry; psychological medicine; psychopathology (the branch of medicine dealing with the diagnosis and treatment of mental disorders)

Sense 3

Meaning:

The relation between selected values of x and observed values of y (from which the most probable value of y can be predicted for any value of x)

Classified under:

Nouns denoting cognitive processes and contents

Synonyms:

regression; regression toward the mean; simple regression; statistical regression

Hypernyms ("regression" is a kind of...):

statistical method; statistical procedure (a method of analyzing or representing statistical data; a procedure for calculating a statistic)

Domain category:

statistics (a branch of applied mathematics concerned with the collection and interpretation of quantitative data and the use of probability theory to estimate population parameters)

Hyponyms (each of the following is a kind of "regression"):

linear regression; rectilinear regression (the relation between variables when the regression equation is linear: e.g., y = ax + b)

curvilinear regression (the relation between variables when the regression equation is nonlinear (quadratic or higher order))

Holonyms ("regression" is a part of...):

regression analysis (the use of regression to make quantitative predictions of one variable from the values of another)

Sense 4

Meaning:

Returning to a former state

Classified under:

Nouns denoting acts or actions

Synonyms:

regress; regression; retrogression; retroversion; reversion

Hypernyms ("regression" is a kind of...):

reversal (a change from one state to the opposite state)

Derivation:

regress (go back to a previous state)

 Context examples 

This may result in an inhibition of both tumor growth and angiogenesis, and eventually lead to tumor regression.

(Cabozantinib, NCI Thesaurus)

EGFR/HER2 kinase inhibitor TAK-285 binds to and inhibits EGFR and HER2, which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors.

(EGFR/HER2 Kinase Inhibitor TAK-285, NCI Thesaurus)

Doxorubicin intercalates between DNA base pairs and interferes with topoisomerase II activity, which inhibits both DNA replication and RNA synthesis, resulting in cancer cell death and tumor regression.

(Glutathione Pegylated Liposomal Doxorubicin Hydrochloride Formulation 2B3-101, NCI Thesaurus)

Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression.

(Flutamide, NCI Thesaurus)

Inhibition of these RTKs may result in an inhibition of tumor growth and angiogenesis, and eventually tumor regression in tumor cells overexpressing these RTKs.

(Famitinib, NCI Thesaurus)

IL-12 may potentiate antitumoral functions of the host immune system, resulting in immune-mediated tumor regression.

(EGEN-001, NCI Thesaurus)

This may result in the inhibition of tumor growth and angiogenesis, and tumor regression.

(Multitargeted Tyrosine Kinase Inhibitor XL647, NCI Thesaurus)

Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression.

(Bexarotene, NCI Thesaurus)

A calcium salt formulation of pitavastatin, a novel statin that induces plaque regression and elevates HDL-cholesterol levels.

(Pitavastatin Calcium, NCI Thesaurus)

This targeted immunotherapy led to cancer regression in the patient in the study.

(Cellular immunotherapy targets a common human cancer mutation, NIH)