English Dictionary

RECOMBINANT PROTEIN

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 Dictionary entry overview: What does recombinant protein mean? 

RECOMBINANT PROTEIN (noun)
  The noun RECOMBINANT PROTEIN has 1 sense:

1. a protein derived from recombinant DNAplay

  Familiarity information: RECOMBINANT PROTEIN used as a noun is very rare.


 Dictionary entry details 


RECOMBINANT PROTEIN (noun)


Sense 1

Meaning:

A protein derived from recombinant DNA

Classified under:

Nouns denoting substances

Hypernyms ("recombinant protein" is a kind of...):

protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)


 Context examples 


A recombinant protein consisting of the hu14.18 monoclonal antibody fused to the cytokine interleukin-2 (IL2) with potential antineoplastic activity.

(Hu14.18-IL2 Fusion Protein, NCI Thesaurus)

A recombinant protein consisting of the cytokine interleukin-2 (IL-2) fused to a humanized soluble T-cell receptor (TCR) directed against a tumor suppressor p53-derived antigen with potential immunopotentiating and antineoplastic activities.

(IL-2 Recombinant Fusion Protein ALT-801, NCI Thesaurus)

A glycosylated recombinant protein which is chemically identical to or similar to endogenous human interleukin-7 (IL-7) with hematopoietic and immunopotentiating activities.

(Glycosylated Recombinant Human Interleukin-7, NCI Thesaurus)

A cytotoxic recombinant protein consisting of interleukin-2 (IL-2) protein sequences fused to diphtheria toxin.

(Denileukin diftitox, NCI Thesaurus)

An insect cell-infecting virus that is used extensively in expression systems for recombinant proteins that require eucaryotic processing systems.

(Baculovirus Expression System, NCI Thesaurus)

A laboratory procedure where the gene encoding a therapeutic recombinant protein is manipulated to minimize the immunogenicity of the protein.

(Deimmunization, NCI Thesaurus)

Includes recombinant proteins, monoclonal antibodies, and nucleic acids.

(Biological agent, NCI Thesaurus)

The recombinant protein molecule SA-4-1BBL has been used to enhance the therapeutic efficacy of cancer vaccines with success in pre-clinical animal models.

(Immune Stimulant Molecule Protects against Cancer Development, The Titi Tudorancea Bulletin)

A recombinant protein consisting of human interleukin 3 (IL3) fused to the first 388 amino acids of diphtheria toxin [DT(388)] with potential antineoplastic activity.

(DT(388)IL3 Fusion Protein, NCI Thesaurus)

A cell-based vaccine composed of previously frozen autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells.

(APC8015F, NCI Thesaurus)



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