PHENELZINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does phenelzine mean? 

• PHENELZINE (noun)
  The noun PHENELZINE has 1 sense:

1. monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression

  Familiarity information: PHENELZINE used as a noun is very rare.

 Dictionary entry details 

• PHENELZINE (noun)

Sense 1

Meaning:

Monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression

Classified under:

Nouns denoting man-made objects

Synonyms:

Nardil; phenelzine

Hypernyms ("phenelzine" is a kind of...):

MAOI; monoamine oxidase inhibitor (any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate)

 Context examples 

In addition, through its primary metabolite phenylethylidenehyrazine (PEH), phenelzine causes elevated GABA levels in the caudate-putamen and nucleus accumbens thereby exerting its anxiolytic effects.

(Phenelzine Sulfate, NCI Thesaurus)

Phenelzine sulfate irreversibly binds to MAO, thereby blocking the oxidative deamination of monoamines resulting in an increased concentration of biogenic amines and a concurrent decrease in catabolism of monoamine neurotransmitters, norepinephrine and serotonin, in the brain.

(Phenelzine Sulfate, NCI Thesaurus)