LEUCINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does leucine mean? 

• LEUCINE (noun)
  The noun LEUCINE has 1 sense:

1. a white crystalline amino acid occurring in proteins that is essential for nutrition; obtained by the hydrolysis of most dietary proteins

  Familiarity information: LEUCINE used as a noun is very rare.

 Dictionary entry details 

• LEUCINE (noun)

Sense 1

Meaning:

A white crystalline amino acid occurring in proteins that is essential for nutrition; obtained by the hydrolysis of most dietary proteins

Classified under:

Nouns denoting substances

Hypernyms ("leucine" is a kind of...):

essential amino acid (an amino acid that is required by animals but that they cannot synthesize; must be supplied in the diet)

 Context examples 

The 1,352-aa protein contains a C-terminal leucine zipper domain and a ribosomal protein S14 signature domain.

(Neuroblastoma-Amplified Sequence, NCI Thesaurus)

This protein is comprised of the transactivation domain of the RNA-binding protein EWS followed by the DNA-binding basic domain and leucine zipper dimerization domain of the cyclic AMP-responsive element-binding protein 1.

(EWSR1/CREB1 Fusion Protein, NCI Thesaurus)

Leucine zippers are present in many gene regulatory proteins, including CREB proteins, Jun/AP1 transcription factors, and FOS-type proteins, as well as MYC proteins.

(MYC Family Gene, NCI Thesaurus)

Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper.

(DNA Binding Protein, NCI Thesaurus)

An N-terminal leucine zipper mediates dimerization of H4 protein and this dimerization is essential to transforming activity.

(D10S170 Protein, NCI Thesaurus)

Sulforaphane activates the transcription factor NF-E2-related factor 2 (Nrf2), a member of the basic leucine zipper family, which binds to and activates antioxidant-response elements (AREs).

(Broccoli sprout extract, NCI Thesaurus)

This protein is comprised of all but the last 4 amino acids of the phosphatidylinositol-binding clathrin assembly protein fused to the C-terminal leucine zipper domain of protein AF-10.

(PICALM/MLLT10 Fusion Protein, NCI Thesaurus)

An L-leucine derivative of melphalan with antineoplastic activity.

(Asaley, NCI Thesaurus)

PTC1 oncogene involves fusion of RET kinase to the H4 dimerization leucine zipper.

(Oncogene RET, NCI Thesaurus)

This protein is comprised of the transactivation domain of the RNA-binding protein EWS followed by the DNA-binding basic domain and leucine zipper dimerization domain of the DNA damage-inducible transcript 3 protein.

(EWSR1/DDIT3 Fusion Protein, NCI Thesaurus)