ISOCARBOXAZID

Pronunciation (US):

(GB):

 Dictionary entry overview: What does isocarboxazid mean? 

• ISOCARBOXAZID (noun)
  The noun ISOCARBOXAZID has 1 sense:

1. a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression

  Familiarity information: ISOCARBOXAZID used as a noun is very rare.

 Dictionary entry details 

• ISOCARBOXAZID (noun)

Sense 1

Meaning:

A monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression

Classified under:

Nouns denoting man-made objects

Synonyms:

isocarboxazid; Marplan

Hypernyms ("isocarboxazid" is a kind of...):

MAOI; monoamine oxidase inhibitor (any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate)

 Context examples 

The down-regulation of central beta-adrenergic and serotonergic receptors by chronic inhibition of MAO may also contribute to the antidepressant effects seen by isocarboxazid.

(Isocarboxazid, NCI Thesaurus)

Isocarboxazid blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine (5-HT) at central aminergic receptors.

(Isocarboxazid, NCI Thesaurus)