HYPERSENSITIVITY

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 Dictionary entry overview: What does hypersensitivity mean? 

• HYPERSENSITIVITY (noun)
  The noun HYPERSENSITIVITY has 2 senses:

1. pathological sensitivity

2. extreme sensitivity

  Familiarity information: HYPERSENSITIVITY used as a noun is rare.

 Dictionary entry details 

• HYPERSENSITIVITY (noun)

Sense 1

Meaning:

Pathological sensitivity

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("hypersensitivity" is a kind of...):

predisposition; sensitivity (susceptibility to a pathogen)

Hyponyms (each of the following is a kind of "hypersensitivity"):

cryaesthesia; cryesthesia (hypersensitivity to cold)

hypersensitivity reaction (an inappropriate and excessive reaction to an allergen (as pollen or dust or animal hair or certain foods); severity ranges from mild allergy to severe systemic reactions leading to anaphylactic shock)

Derivation:

hypersensitive (having an allergy or peculiar or excessive susceptibility (especially to a specific factor))

Sense 2

Meaning:

Extreme sensitivity

Classified under:

Nouns denoting cognitive processes and contents

Hypernyms ("hypersensitivity" is a kind of...):

sensibility; sensitiveness; sensitivity ((physiology) responsiveness to external stimuli; the faculty of sensation)

Derivation:

hypersensitive (having an allergy or peculiar or excessive susceptibility (especially to a specific factor))

 Context examples 

As a non-specific immunostimulant, Corynebacterium granulosum P40 activates the reticuloendothelial system, induces the production of certain cytokines, enhances macrophage activity, and potentiates a delayed-type hypersensitivity response when co-administered with an antigen.

(Corynebacterium Granulosum P40, NCI Thesaurus)

Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign.

(Delayed-Type Hypersensitivity, NCI Thesaurus)

A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one or more internal organs.

(Drug Hypersensitivity Syndrome, NCI Thesaurus)

This permits the administration of larger doses of docetaxel and improves the drug's safety profile by avoiding solvent-associated toxicities, such as hypersensitivity reactions and neurotoxicity.

(Nanosomal Docetaxel Lipid Suspension, NCI Thesaurus)

C5a is the most potent anaphylatoxin, mediating immediate hypersensitivity.

(C5a, NCI Thesaurus)

Cromolyn sodium probably interferes with the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions.

(Cromolyn Sodium, NCI Thesaurus)

A form of drug hypersensitivity syndrome caused by anti-convulsants.

(Anticonvulsant Hypersensitivity Syndrome, NCI Thesaurus)

The E. carotovora-derived form of asparaginase is typically reserved for cases of asparaginase hypersensitivity.

(Asparaginase, NCI Thesaurus)

A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response.

(Anaphylaxis, NCI Thesaurus/CTCAE)

A skin hypersensitivity reaction characterized by raised purpuric lesions, red macules, hemorrhagic blisters and ulcerations.

(Drug Induced Cutaneous Vasculitis, NCI Thesaurus)