HYALURONIDASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does hyaluronidase mean? 

• HYALURONIDASE (noun)
  The noun HYALURONIDASE has 1 sense:

1. an enzyme (trade name Hyazyme) that splits hyaluronic acid and so lowers its viscosity and increases the permeability of connective tissue and the absorption of fluids

  Familiarity information: HYALURONIDASE used as a noun is very rare.

 Dictionary entry details 

• HYALURONIDASE (noun)

Sense 1

Meaning:

An enzyme (trade name Hyazyme) that splits hyaluronic acid and so lowers its viscosity and increases the permeability of connective tissue and the absorption of fluids

Classified under:

Nouns denoting substances

Synonyms:

hyaluronidase; Hyazyme; spreading factor

Hypernyms ("hyaluronidase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

 Context examples 

The chondroblast secretes hyaluronidase, chondroitin sulfates, and collagen II to form a collagen matrix.

(Chondroblast, NCI Thesaurus)

A pegylated formulation of a recombinant form of human hyaluronidase with potential antitumor activity.

(Pegylated Recombinant Human Hyaluronidase PH20, NCI Thesaurus)

A highly purified preparation of ovine testicular hyaluronidase with potential chemoadjuvant activity.

(Hyaluronidase, Ovine, NCI Thesaurus)

Upon subcutaneous administration, hyaluronidase modifies the permeability of connective tissue by hydrolyzing hyaluronic acid.

(Hyaluronidase, NCI Thesaurus)

Furthermore, echinacoside, one of the components in Echinacea extract, has been shown to inhibit hyaluronidase, whose action increases tissue permeability, thereby Echinacea extract may promote tissue growth for wound healing by preventing bacteria spreading into healthy cells.

(Echinacea Extract, NCI Thesaurus)