FLUOROURACIL

Pronunciation (US):

(GB):

 Dictionary entry overview: What does fluorouracil mean? 

• FLUOROURACIL (noun)
  The noun FLUOROURACIL has 1 sense:

1. an antimetabolite used to treat certain cancers

  Familiarity information: FLUOROURACIL used as a noun is very rare.

 Dictionary entry details 

• FLUOROURACIL (noun)

Sense 1

Meaning:

An antimetabolite used to treat certain cancers

Classified under:

Nouns denoting man-made objects

Hypernyms ("fluorouracil" is a kind of...):

antimetabolite (an antineoplastic drug that inhibits the utilization of a metabolite)

 Context examples 

A regimen consisting of epirubicin, followed by cyclophosphamide, methotrexate, fluorouracil (CMF), used in the adjuvant setting for the treatment of breast cancer.

(E-CMF Regimen, NCI Thesaurus)

Upon intracerebral injection, E. coli CD-expressing genetically modified NSCs express the E. coli cytosine deaminase, an enzyme that catalyzes the intracellular conversion of the nontoxic prodrug 5-fluorocytosine (5-FC) into the cytotoxic 5-fluorouracil (5-FU).

(E. coli CD-expressing Genetically Modified Neural Stem Cells, NCI Thesaurus)

Hereditary defects in the DPYD gene cause an error in pyrimidine metabolism associated with both thymine-uraciluria and increased toxicity of 5-fluorouracil during chemotherapy.

(DPYD wt Allele, NCI Thesaurus)

It includes the drugs fluorouracil and leucovorin calcium.

(de Gramont regimen, NCI Dictionary)

A fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.

(Doxifluridine, NCI Thesaurus)

A regimen consisting of epirubicin, cisplatin and fluorouracil used alone or with radiation for the treatment of advanced-stage gastric cancer.

(ECF Regimen, NCI Thesaurus)

Also called 5-fluorouracil, 5-FU, Adrucil, Fluoroplex, and fluorouracil.

(Efudex, NCI Dictionary)

A regimen consisting of cisplatin, epirubicin, leucovorin and fluorouracil used for the treatment of advanced-stage gastric cancer.

(PELF Regimen, NCI Thesaurus)

A regimen consisting of cisplatin, continuous infusion fluorouracil and leucovorin used as an induction treatment for squamous cell head and neck cancer.

(PFL Regimen, NCI Thesaurus)

A substance that is being studied for its ability to increase the effectiveness of the anticancer drug fluorouracil.

(PALA, NCI Dictionary)