FAS

Pronunciation (US):

(GB):

 Dictionary entry overview: What does FAS mean? 

• FAS (noun)
  The noun FAS has 1 sense:

1. a congenital medical condition in which body deformation occurs or facial development or mental ability is impaired because the mother drinks alcohol during pregnancy

  Familiarity information: FAS used as a noun is very rare.

 Dictionary entry details 

• FAS (noun)

Sense 1

Meaning:

A congenital medical condition in which body deformation occurs or facial development or mental ability is impaired because the mother drinks alcohol during pregnancy

Classified under:

Nouns denoting stable states of affairs

Synonyms:

FAS; fetal alcohol syndrome

Hypernyms ("FAS" is a kind of...):

syndrome (a pattern of symptoms indicative of some disease)

 Context examples 

Fas ligand binding to Fas between B and T cells may negatively modulate B cell activation, inducing apoptosis that limits B cell proliferation and activation.

(Antigen Dependent B Cell Activation Pathway, NCI Thesaurus/BIOCARTA)

Human FAS wild-type allele is located in the vicinity of 10q24.1 and is approximately 26 kb in length.

(FAS wt Allele, NCI Thesaurus)

Keratinocyte differentiation studies have identified and provided significant detail regarding the involvement of three of the 4 major MAP kinase pathways from several diverse stimuli such as EGF, FAS, TNF and calcium influx.

(Keratinocyte Differentiation Pathway, NCI Thesaurus/BIOCARTA)

Fas is a receptor in the TNF receptor gene family that induces apoptosis when stimulated by its cell-bound ligand, Fas-ligand.

(HSP27 Regulation Pathway, NCI Thesaurus/BIOCARTA)

Fas signaling is also involved in immune surveillance to remove transformed cells and virus infected cells.

(Fas Signaling Pathway BioCarta, NCI Thesaurus/BIOCARTA)

This protein is an inhibitor of apoptosis induced by TNF or FAS pathways, as well as p53-mediated apoptosis.

(E1B Protein, NCI Thesaurus)

Apoptosis, programmed cell death, is triggered by a variety of stimuli, including cell surface receptors like FAS, mitochondrial response to stress, and cytotoxic T cells.

(Caspase Cascade Pathway, NCI Thesaurus/BIOCARTA)

Fas antigen is a member of tumor necrosis factor family that mediates antibody-triggered apoptosis.

(Monoclonal Antibody 7C11, NCI Thesaurus)

Bound to TGFBR2 and TNFRSF6 FAS death domain via C-terminus, DAXX bridges apoptotic FAS activation with caspase-independent ASK1 activation of JNK.

(Death Domain-Associated Protein 6, NCI Thesaurus)

Acts as an adaptor protein, interacting with FAS or TNFR-2.

(Fas-Associated Via Death Domain, NCI Thesaurus)