ER

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does ER mean? 

• ER (noun)
  The noun ER has 2 senses:

1. a trivalent metallic element of the rare earth group; occurs with yttrium

2. a room in a hospital or clinic staffed and equipped to provide emergency care to persons requiring immediate medical treatment

  Familiarity information: ER used as a noun is rare.

 Dictionary entry details 

• ER (noun)

Sense 1

Meaning:

A trivalent metallic element of the rare earth group; occurs with yttrium

Classified under:

Nouns denoting substances

Synonyms:

atomic number 68; Er; erbium

Hypernyms ("Er" is a kind of...):

metal; metallic element (any of several chemical elements that are usually shiny solids that conduct heat or electricity and can be formed into sheets etc.)

Holonyms ("Er" is a substance of...):

fergusonite (a dark mineral consisting of oxides of yttrium and erbium and tantalum and other minerals)

gadolinite; ytterbite (a mineral that is a source of rare earths; consists of silicates of iron and beryllium and cerium and yttrium and erbium)

Sense 2

Meaning:

A room in a hospital or clinic staffed and equipped to provide emergency care to persons requiring immediate medical treatment

Classified under:

Nouns denoting man-made objects

Synonyms:

emergency room; ER

Hypernyms ("ER" is a kind of...):

hospital room (a room in a hospital for the care of patients)

 Context examples 

Cancer cells that are ER- do not need estrogen to grow, and usually do not stop growing when treated with hormones that block estrogen from binding.

(ER-, NCI Dictionary)

Cancer cells that are ER+ may need estrogen to grow, and may stop growing or die when treated with substances that block the binding and actions of estrogen.

(ER+, NCI Dictionary)

Approximately 30% of breast carcinomas lack ER expression.

(MTA3 Pathway, NCI Thesaurus/BIOCARTA)

If the native structure of the glycoprotein cannot be achieved it is retained in the ER.

(Endoplasmic Reticulum Degradation Pathway, NCI Thesaurus/BIOCARTA)

They usually take you to the ER for more care.

(Emergency Medical Services, NIH)

As a result, a caspase-independent and endoplasmic reticulum (ER) stress-induced mu-calpain-mediated cell death occurs in NQO1-overexpressing tumor cells.

(Beta-lapachone Prodrug ARQ 761, NCI Thesaurus)

IP3 binds to a receptor in the ER to cause the release of intracellular calcium, and the subsequent activation of protein kinase C, calmodulin-dependent pathways.

(Bioactive Peptide Signaling Pathway, NCI Thesaurus/BIOCARTA)

Intracellular calcium levels are also increased in response to phospholipase C activation, producing IP3 and releasing calcium from stores in the ER.

(Calcineurin Pathway, NCI Thesaurus/BIOCARTA)

After sequential addition of monosaccharides by ALG glycosyltransferases, the N-glycan precursor is attached by the OST (oligosaccharyltransferase) complex to the polypeptide chain that is being synthesized and translocated through the ER membrane.

(N-Glycan Biosynthesis Pathway, NCI Thesaurus/KEGG)

A second possibility would involve a scaffold protein that interacts with ER.

(Pelp1 Estrogen Receptor Pathway, NCI Thesaurus/BIOCARTA)