ENDPOINT

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 Dictionary entry overview: What does endpoint mean? 

• ENDPOINT (noun)
  The noun ENDPOINT has 1 sense:

1. a place where something ends or is complete

  Familiarity information: ENDPOINT used as a noun is very rare.

 Dictionary entry details 

• ENDPOINT (noun)

Sense 1

Meaning:

A place where something ends or is complete

Classified under:

Nouns denoting spatial position

Synonyms:

end point; endpoint; termination; terminus

Hypernyms ("endpoint" is a kind of...):

end; terminal (either extremity of something that has length)

 Context examples 

One endpoint of CXCR4 signaling is the activation of transcription factors such as AP-1 and chemokine regulated genes.

(CXCR4 Signaling Pathway, NCI Thesaurus/BIOCARTA)

The primary endpoint of the study was major cardiovascular disease, defined as a combined endpoint of myocardial infarction, stroke or fatal cardiovascular disease.

(Eating Regular Variety of Nuts Associated with Lower Risk of Heart Disease, The Titi Tudorancea Bulletin)

The endpoints of a clinical trial are usually included in the study objectives.

(End Point, NCI Dictionary)

An endpoint of the Map kinase pathway is modification of transcription factor activity, such as activation of ELK transcription factors.

(IGF-1 Signaling Pathway, NCI Thesaurus/BIOCARTA)

Randomized, controlled clinical trial with total mortality as an endpoint.

(Level of Evidence 1A, NCI Dictionary)

The endpoints of these cascades include the MAPK activated protein kinases (MAPKAPK) and some of the numerous transcription factors that regulate genes involved in apoptosis, inflammation, cell growth and differentiation.

(MAPKinase Signaling Pathway, NCI Thesaurus/BIOCARTA)

Either of the two numbers that specify the endpoints of a confidence interval.

(Confidence Limit, NCI Thesaurus)

It is commonly used as a primary endpoint in stroke treatment studies.

(Modified Rankin Scale, NCI Thesaurus)

Clinical endpoints are distinct measurements or analyses of disease characteristics observed in a study or a clinical trial that reflect the effect of a therapeutic intervention.

(Clinical Endpoint, NCI Thesaurus)

An external committee whose purpose is to evaluate study data and decide whether a study endpoint or other criterion has been met.

(Adjudication Committee, NCI Thesaurus)