DEOXYGUANOSINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does deoxyguanosine mean? 

• DEOXYGUANOSINE (noun)
  The noun DEOXYGUANOSINE has 1 sense:

1. a nucleoside component of DNA; composed of guanine and deoxyribose

  Familiarity information: DEOXYGUANOSINE used as a noun is very rare.

 Dictionary entry details 

• DEOXYGUANOSINE (noun)

Sense 1

Meaning:

A nucleoside component of DNA; composed of guanine and deoxyribose

Classified under:

Nouns denoting substances

Synonyms:

deoxyguanosine; guanosine

Hypernyms ("deoxyguanosine" is a kind of...):

nucleoside (a glycoside formed by partial hydrolysis of a nucleic acid)

 Context examples 

Forodesine binds preferentially to and inhibits purine nucleotide phosphorylase (PNP), resulting in the accumulation of deoxyguanosine triphosphate and the subsequent inhibition of the enzyme ribonucleoside diphosphate reductase and DNA synthesis.

(Forodesine hydrochloride, NCI Thesaurus)

A synthetic analog of 2-deoxyguanosine with antiviral activity against hepatitis B virus (HBV).

(Entecavir, NCI Thesaurus)

Highly specific for dGTP, producing deoxyguanosine and inorganic tripolyphosphate.

(dGTPase, NCI Thesaurus)

An anhydrous formulation of entecavir, a synthetic analog of 2-deoxyguanosine with antiviral activity against hepatitis B virus (HBV).

(Entecavir Anhydrous, NCI Thesaurus)

This compound also forms mutagenic DNA adducts when it reacts with deoxyadenosine and deoxyguanosine in DNA.

(Malondialdehyde, NCI Thesaurus)

In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding.

(Penciclovir, NCI Thesaurus)

In turn, the triphosphate form competes with the natural substrate deoxyguanosine triphosphate (dGTP) for incorporation into viral DNA.

(Entecavir, NCI Thesaurus)

Deoxyguanosine triphosphate (dGTP) triphosphohydrolase (EC 3.1.5.1).

(dGTPase, NCI Thesaurus)