TOPICAL

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does topical mean? 

• TOPICAL (adjective)
  The adjective TOPICAL has 3 senses:

1. pertaining to the surface of a body part

2. of or relating to or arranged by topics

3. of interest at the present time

  Familiarity information: TOPICAL used as an adjective is uncommon.

 Dictionary entry details 

• TOPICAL (adjective)

Sense 1

Meaning:

Pertaining to the surface of a body part

Context example:

a topical anesthesia

Similar:

local (affecting only a restricted part or area of the body)

Domain category:

medical specialty; medicine (the branches of medical science that deal with nonsurgical techniques)

Sense 2

Meaning:

Of or relating to or arranged by topics

Classified under:

Relational adjectives (pertainyms)

Context example:

a detailed record on both a chronological and a topical basis

Pertainym:

topic (some situation or event that is thought about)

Derivation:

topic (some situation or event that is thought about)

topic (the subject matter of a conversation or discussion)

Sense 3

Meaning:

Of interest at the present time

Context example:

a topical and timely study of civil liberty

Similar:

current (occurring in or belonging to the present time)

 Context examples 

Following topical ocular administration, brinzolamide inhibits carbonic anhydrase II, an enzyme that is responsible for the movement of sodium and fluid transport in the eye.

(Brinzolamide, NCI Thesaurus)

The drug action is mostly topical/local.

(Auricular Route of Administration, NCI Thesaurus)

Passing through the skin, as an injection or a topical medicine.

(Percutaneous, NCI Dictionary)

Motretinide is used as a topical agent in the treatment of acne.

(Motretinide, NCI Thesaurus)

Camphor is used in topical anti-infective and anti-pruritic (anti-itching) agents.

(Camphor, NCI Dictionary)

A topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties.

(Medrysone, NCI Thesaurus)

A topical cream formulation containing the hydrochloride salt of methyl-5-aminolevulinate, a lipophilic methyl ester of 5-aminolevulinic acid, with photosensitizer prodrug activity.

(Methyl-5-Aminolevulinate Hydrochloride Cream, NCI Thesaurus)

The approach site might be mouth, but from a route code perspective, this could include: swallow, oral rinse, oral topical application, chew, oral dissolve, oral inhalation (via intermittent flow or rebreather mask).

(Performed Substance Administration Route Of Administration Code, NCI Thesaurus/BRIDG)

Used for open angle glaucoma and eye hypertension, topical administration decreases intraocular pressure with minimal effect on cardiovascular parameters, reducing aqueous humor production and increasing uveoscleral outflow.

(Brimodine, NCI Thesaurus)

Upon topical application of F511 cream, aluminium chlorohydrate forms a gel matrix in the sweat gland which subsequently reduces, then stops the flow of water.

(Antiperspirant Cream F511, NCI Thesaurus)