REQUIRED

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does required mean? 

• REQUIRED (adjective)
  The adjective REQUIRED has 2 senses:

1. necessary for relief or supply

2. required by rule

  Familiarity information: REQUIRED used as an adjective is rare.

 Dictionary entry details 

• REQUIRED (adjective)

Sense 1

Meaning:

Necessary for relief or supply

Synonyms:

needed; needful; required; requisite

Context example:

provided them with all things needful

Similar:

necessary (absolutely essential)

Sense 2

Meaning:

Required by rule

Synonyms:

compulsory; mandatory; required

Context example:

required reading

Similar:

obligatory (morally or legally constraining or binding)

 Context examples 

DLL4 is the only Notch ligand selectively expressed on endothelial cells; DLL4/Notch signaling is required for the development of functional tumor blood vessels.

(Anti-Dll4 Monoclonal Antibody REGN421, NCI Thesaurus)

Shortly after breakfast Henry left them for Woodston, where business required and would keep him two or three days.

(Northanger Abbey, by Jane Austen)

This protein is required for cell proliferation.

(Antigen KI-67, NCI Thesaurus)

The expression of DLL4 is highly restricted to the vascular endothelium; DLL4/Notch signaling is required for the development of functional tumor blood vessels.

(Anti-DLL4 Monoclonal Antibody MEDI0639, NCI Thesaurus)

They had no conversation together, no intercourse but what the commonest civility required.

(Persuasion, by Jane Austen)

One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth.

(AMSH Protein, NCI Thesaurus/LocusLink)

A required early step in cancer growth and metastasis.

(Angiogenic Switch, NCI Thesaurus)

This allele, which encodes serine/threonine-protein kinase ATR protein, plays an essential role in cell cycle checkpoints required for cell cycle arrest and DNA damage repair in response to DNA damage.

(ATR wt Allele, NCI Thesaurus)

She saw decision in his looks, and her surprise and vexation required some minutes' silence to be settled into composure.

(Mansfield Park, by Jane Austen)

Emma found that she must wait; and now it required little effort.

(Emma, by Jane Austen)