UROKINASE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does urokinase mean? 

• UROKINASE (noun)
  The noun UROKINASE has 1 sense:

1. protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis

  Familiarity information: UROKINASE used as a noun is very rare.

 Dictionary entry details 

• UROKINASE (noun)

Sense 1

Meaning:

Protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis

Classified under:

Nouns denoting substances

Synonyms:

plasminogen activator; urokinase

Hypernyms ("urokinase" is a kind of...):

peptidase; protease; proteinase; proteolytic enzyme (any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis)

 Context examples 

This allele, which encodes urokinase plasminogen activator surface receptor protein, plays a role in the regulation of both cell-surface plasminogen activation and localized degradation of the extracellular matrix.

(PLAUR wt Allele, NCI Thesaurus)

A6 is a small piece of a protein called urokinase (an enzyme that dissolves blood clots or prevents them from forming).

(A6, NCI Dictionary)

Plasminogen activator inhibitor 1 (PAI1) and plasminogen activator inhibitor 2 (PAI2) inhibit cleavage of plasminogen by tissue-type plasminogen activator (tPA) or urokinase plasminogen activator (uPA).

(Fibrinolysis Pathway, NCI Thesaurus/BIOCARTA)

Synthesized and secreted locally from vascular endothelial cells; primary physiologic inhibitor of tissue plasminogen activator; also inhibits urokinase; implicated in thrombotic and hemorrhagic disorders.

(Plasminogen Activator Inhibitor, NIH CRISP Thesaurus)

Also called urokinase plasminogen activator (uPA)-derived peptide A6.

(A6, NCI Dictionary)