UNBOUND

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does unbound mean? 

• UNBOUND (adjective)
  The adjective UNBOUND has 3 senses:

1. not secured within a cover

2. not restrained or tied down by bonds

3. not held in chemical or physical combination

  Familiarity information: UNBOUND used as an adjective is uncommon.

 Dictionary entry details 

• UNBOUND (adjective)

Sense 1

Meaning:

Not secured within a cover

Context example:

an unbound book

Similar:

looseleaf (being or having leaves that can be easily removed or rearranged)

Antonym:

bound (secured with a cover or binding; often used as a combining form)

Sense 2

Meaning:

Not restrained or tied down by bonds

Similar:

unchained; unfettered; unshackled; untied (not bound by shackles and chains)

untethered (not confined or restricted with a tether)

Also:

free (not limited or hampered; not under compulsion or restraint)

Antonym:

bound (confined by bonds)

Sense 3

Meaning:

Not held in chemical or physical combination

Similar:

free (unconstrained or not chemically bound in a molecule or not fixed and capable of relatively unrestricted motion)

 Context examples 

A measurement of the free, unbound cortisol in a biological specimen.

(Free Cortisol Measurement, NCI Thesaurus/CDISC)

The determination of the amount of free, unbound cortisol present in a sample.

(Free Cortisol Measurement, NCI Thesaurus)

This results in low levels of free iron and decreases inorganic, unbound iron-related toxicities thereby allowing for administration of higher doses of iron as compared to other iron-containing formulations.

(Iron Isomaltoside 1000, NCI Thesaurus)

DTPA may chelate metallic moieties of unbound, extracellular radioimmunotherapeutics, thereby aggregating radioimmunotherapeutics locally to higher concentrations, and improving tumor cell radiocytotoxicity, while sparing normal tissues from the radiocytotoxic effects.

(Pentetic Acid, NCI Thesaurus)

A measurement of the amount of unbound glycerol in a biological specimen.

(Free Glycerol Measurement, NCI Thesaurus/CDISC)

Compared to the administration of unbound TNF, colloidal gold-bound TNF may improve the efficacy and safety of TNF administration by delivering TNF specifically to tumor tissue.

(Colloidal gold-bound tumor necrosis factor, NCI Thesaurus)

We belayed the fore down-haul; but the sail was split, and we hauled down the yard, and got the sail into the ship, and unbound all the things clear of it.

(Gulliver's Travels into several remote nations of the world, by Jonathan Swift)

And as he felt pity for them, he raised the ladder, and climbed up, unbound one of them after the other, and brought down all seven.

(Fairy Tales, by The Brothers Grimm)

They showed that the unbound spike actually shifts among 3 distinct configurations.

(The Structure and Dynamics of HIV Surface Spikes, NIH)

Pentetic acid chelates with the metallic radioisotopic moieties of unbound, extracellular radioimmunotherapeutic agents, resulting in higher specific tumor cell binding of radioimmunotherapeutic agents; this results in improved tumor cell radiocytotoxicity and the sparing of normal cells and tissues from the radiocytotoxic effects of these agents.

(Pentetic acid calcium, NCI Thesaurus)