TRYPSIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does trypsin mean? 

• TRYPSIN (noun)
  The noun TRYPSIN has 1 sense:

1. an enzyme of pancreatic origin; catalyzes the hydrolysis of proteins to smaller polypeptide units

  Familiarity information: TRYPSIN used as a noun is very rare.

 Dictionary entry details 

• TRYPSIN (noun)

Sense 1

Meaning:

An enzyme of pancreatic origin; catalyzes the hydrolysis of proteins to smaller polypeptide units

Classified under:

Nouns denoting substances

Hypernyms ("trypsin" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "trypsin"):

trypsinogen (inactive precursor of trypsin; a substance secreted by the pancreas and converted to active trypsin by enterokinase in the small intestine)

 Context examples 

This protein plays a role in the modulation of trypsin activity.

(Pancreatic Secretory Trypsin Inhibitor, NCI Thesaurus)

This allele, which encodes kallikrein-11 protein, is involved in the proteolytic cleavage of substrates for both kallikrein and trypsin.

(KLK11 wt Allele, NCI Thesaurus)

One Kallikrein Inhibitor Unit is equal to 0.025 antiplasmin units or 0.0031 trypsin inhibitor units.

(Kallikrein Inhibitor Unit, NCI Thesaurus)

This species is leucine arylamidase positive, lipase and trypsin negative, nonsporulating, non-motile, produces acid from ribose, glucose, mannose, cellobiose and salicin but not from maltose, lactose, trehalose, esculin or amygdalin.

(Collinsella intestinalis, NCI Thesaurus)

Bowman-Birk inhibitor contains distinct inhibitory sites for trypsin and chymotrypsin.

(Bowman-Birk inhibitor concentrate, NCI Thesaurus)

The research team then treated esophageal tissue samples with alpha-1 anti-trypsin, or A1AT, a drug approved to treat an inherited form of emphysema.

(Eosinophilic esophagitis may be due to missing protein, National Institutes of Health)

Pancreatic proteolytic enzymes include trypsin, chymotrypsin and carboxypeptidase; these enzymes are secreted as zymogens, inactive precursors of the enzymes, and are activated in the lumen of the digestive canal.

(Pancreatic Proteolytic Enzymes, NCI Thesaurus)

As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively and reversibly inhibits the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator, and tissue and leukocytic proteinases, resulting in attenuation of the systemic inflammatory response (SIR), fibrinolysis, and thrombin generation.

(Aprotinin, NCI Thesaurus)

Pancreatic secretory trypsin inhibitor (79 aa, ~9 kDa) is encoded by the human SPINK1 gene.

(Pancreatic Secretory Trypsin Inhibitor, NCI Thesaurus)

Another proteolytic enzyme, enteropeptidase, is associated with the brush border of enterocytes; this enzyme catalyses the conversion of trypsinogen into trypsin which, in turn, can activate a number of other pancreatic zymogens.

(Pancreatic Proteolytic Enzymes, NCI Thesaurus)