THREE-FOLD

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does three-fold mean? 

• THREE-FOLD (adjective)
  The adjective THREE-FOLD has 2 senses:

1. three times as great or many

2. having more than one decidedly dissimilar aspects or qualities

  Familiarity information: THREE-FOLD used as an adjective is rare.

 Dictionary entry details 

• THREE-FOLD (adjective)

Sense 1

Meaning:

Three times as great or many

Synonyms:

three-fold; threefold; treble; triple

Context example:

a threefold increase

Similar:

multiple (having or involving or consisting of more than one part or entity or individual)

Sense 2

Meaning:

Having more than one decidedly dissimilar aspects or qualities

Synonyms:

double; dual; three-fold; threefold; treble; two-fold; twofold

Context example:

every episode has its double and treble meaning

Similar:

multiple (having or involving or consisting of more than one part or entity or individual)

 Context examples 

Due to the addition of two carbohydrate chains, darbepoetin alfa exhibits a three-fold greater half-life than does erythropoietin.

(Darbepoetin alfa, NCI Thesaurus)

Community health centers have a three-fold mission.

(Community Health Center, NCI Thesaurus)

Insulin production can increase two- to three-fold, but only when the blood glucose amount is high.

(Researchers Develop Insulin-Producing Cells Activated by Light for Diabetes, The Titi Tudorancea Bulletin)

LY6K is a tumor-associated antigen (TAA) that occurs singly in glycosylphosphatidyl-inositol (GPI)-linked cell-surface glycoproteins or as three-fold repeated domain in the urokinase-type plasminogen activator receptor; VEGFRs are cell surface receptors that stimulate endothelial cell proliferation, invasion, angiogenesis, and vasculogenesis upon ligand binding and receptor activation.

(LY6K/VEGFR1/VEGFR2 Multipeptide Vaccine, NCI Thesaurus)