T LYMPHOCYTE

IPA (US):

 Dictionary entry overview: What does T lymphocyte mean? 

• T LYMPHOCYTE (noun)
  The noun T LYMPHOCYTE has 1 sense:

1. a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells

  Familiarity information: T LYMPHOCYTE used as a noun is very rare.

 Dictionary entry details 

• T LYMPHOCYTE (noun)

Sense 1

Meaning:

A small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells

Classified under:

Nouns denoting body parts

Synonyms:

T cell; T lymphocyte

Hypernyms ("T lymphocyte" is a kind of...):

lymph cell; lymphocyte (an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection)

Hyponyms (each of the following is a kind of "T lymphocyte"):

CD4 cell; CD4 T cell; helper cell; helper T cell (T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus)

CD8 cell; CD8 T cell; cytotoxic T cell; killer cell; killer T cell (T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it)

 Context examples 

After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein, resulting in tumor cell lysis.

(Alpha Fetoprotein Adenoviral Vector Vaccine, NCI Thesaurus)

CD8+ T lymphocytes are one type of T-lymphocyte which bears the CD8 molecular marker on its cell surface.

(Murine CD8-Positive T-Lymphocytes, NCI Thesaurus)

NA17.A2 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen, which may result in a reduction in tumor size.

(NA17.A2 Peptide Vaccine, NCI Thesaurus)

Aldesleukin increases the activity and growth of white blood cells called T lymphocytes and B lymphocytes.

(Aldesleukin, NCI Dictionary)

Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against AFP-expressing cancer cells, resulting in tumor cell lysis.

(Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)

When pulsed with specific tumor associated antigens (TAAs), alphaDC1 is able to induce a potent cytotoxic T lymphocyte (CTL) response against TAAs; as a result it can be used as a cancer vaccine.

(Alpha-type-1 Polarized Dendritic Cells, NCI Thesaurus)

Autologous vaccination with these PBLs stimulates a host cytotoxic T lymphocyte response against ovarian cancer cells that overexpress FBP.

(MOv-PBL Vaccine, NCI Thesaurus)

It is characterized by the presence of small to medium sized T lymphocytes that are cytotoxic and express CD56.

(Monomorphic CD56+ Intestinal T-Cell Lymphoma, NCI Thesaurus)

This may lead to the recruitment of cytotoxic T lymphocytes (CTL) to the T lymphocyte/tumor cell aggregates and result in CTL-mediated death of gp100-expressing melanoma cancer cells.

(Monoclonal T-cell Receptor Anti-CD3 scFv Fusion Protein IMCgp100, NCI Thesaurus)

Vaccination with the neoantigen-based melanoma vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis.

(Neoantigen-based Melanoma-Poly-ICLC Vaccine, NCI Thesaurus)