SINGLET

Pronunciation (US):

(GB):

 Dictionary entry overview: What does singlet mean? 

• SINGLET (noun)
  The noun SINGLET has 1 sense:

1. a collarless men's undergarment for the upper part of the body

  Familiarity information: SINGLET used as a noun is very rare.

 Dictionary entry details 

• SINGLET (noun)

Sense 1

Meaning:

A collarless men's undergarment for the upper part of the body

Classified under:

Nouns denoting man-made objects

Synonyms:

singlet; undershirt; vest

Hypernyms ("singlet" is a kind of...):

undergarment; unmentionable (a garment worn under other garments)

 Context examples 

When laser light is applied, a photodynamic reaction between HPPH and oxygen occurs, resulting in the production of cytotoxic free radicals and singlet oxygen and free radical-mediated cell death.

(HPPH, NCI Thesaurus)

When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect.

(Aminolevulinic acid, NCI Thesaurus)

Within an organism, nanaomycin A is first reduced by flavin or NADH dehydrogenase then rapidly autooxidized leading to the production of singlet molecular oxygen (O2-).

(Nanafrocin, NCI Thesaurus)

Upon exposure to light of appropriate wavelength (red, or blue), PpIX catalyzes oxygen to singlet oxygen, an intracellular toxin, which can further react to form superoxide and hydroxyl radicals.

(Aminolevulinic acid hydrochloride, NCI Thesaurus)

Upon photoirradiation, PpIX is activated and transfers energy to oxygen, generating singlet oxygen and superoxide and hydroxyl radicals, which may result in free-radical-mediated DNA damage and cell death.

(Methyl-5-Aminolevulinate Hydrochloride Cream, NCI Thesaurus)

Upon exposure to light of appropriate wavelength (violet to blue range), excited PpIX emits a characteristic red fluorescence which could facilitate guided resection, and generates excited singlet oxygen molecules that could kill cells when appropriate laser dosage is applied.

(Oral Aminolevulinic Acid Hydrochloride, NCI Thesaurus)

Upon systemic administration, hematoporphyrin derivatives accumulate in tumor cells and, once activated by red laser light (630 nm), in the presence of oxygen, produce singlet oxygen and other reactive oxygen radicals, resulting in local radical-mediated tumor cell death.

(Hematoporphyrin derivative, NCI Thesaurus)

Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects.

(Motexafin lutetium, NCI Thesaurus)