SENSITIZING

Pronunciation (US):

(GB):

 Dictionary entry overview: What does sensitizing mean? 

• SENSITIZING (noun)
  The noun SENSITIZING has 1 sense:

1. rendering an organism sensitive to a serum by a series of injections

  Familiarity information: SENSITIZING used as a noun is very rare.

• SENSITIZING (adjective)
  The adjective SENSITIZING has 1 sense:

1. making susceptible or sensitive to either physical or emotional stimuli

  Familiarity information: SENSITIZING used as an adjective is very rare.

 Dictionary entry details 

• SENSITIZING (noun)

Sense 1

Meaning:

Rendering an organism sensitive to a serum by a series of injections

Classified under:

Nouns denoting acts or actions

Synonyms:

sensitisation; sensitising; sensitization; sensitizing

Hypernyms ("sensitizing" is a kind of...):

immunisation; immunization (the act of making immune (especially by inoculation))

• SENSITIZING (adjective)

Sense 1

Meaning:

Making susceptible or sensitive to either physical or emotional stimuli

Synonyms:

sensitising; sensitizing

Attribute:

predisposition; sensitivity (susceptibility to a pathogen)

Antonym:

desensitizing (making less susceptible or sensitive to either physical or emotional stimuli)

 Context examples 

The resulting complexes accumulate in hypoxic tumors, thereby depleting radioprotective thiol compounds and sensitizing tumor cells to be more susceptible for radiation treatment.

(Pimonidazole, NCI Thesaurus)

In addition, mHtt affects Ca2+ signaling by sensitizing InsP3R1 to activation by InsP3, stimulating NR2B/NR1 NMDAR activity, and destabilizing mitochondrial Ca2+ handling.

(Huntington's Disease Pathway, NCI Thesaurus/KEGG)

Any agent within the glitazar class that are dual or pan-acting peroxisome proliferator-activated receptor (PPAR) agonists with insulin sensitizing and lipid lowering activity.

(Glitazar Antidiabetic Agent, NCI Thesaurus)

These drugs activate PPAR-gamma and repress expression of 11betaHSD-1 in visceral tissue, perhaps accounting in part for the antidiabetic insulin sensitizing properties of these drugs.

(Metabolic Syndrome Pathway, NCI Thesaurus/BIOCARTA)

Exhibiting high electron affinity, misonidazole induces the formation of free radicals and depletes radioprotective thiols, thereby sensitizing hypoxic cells to the cytotoxic effects of ionizing radiation.

(Misonidazole, NCI Thesaurus)

Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia.

(Niacinamide, NCI Thesaurus)

Adenoviral vector encoding HSV thymidine kinase is transduced into tumor cells, sensitizing tumor cells that overexpress HSV-tk to synthetic acyclic guanosine analogues.

(Adenoviral Vector Encoding HSV Thymidine Kinase, NCI Thesaurus)

A molecular genetic abnormality indicating the presence of a sensitizing mutation in the epidermal growth factor receptor-tyrosine kinase inhibitor domain.

(EGFR-TKI Sensitizing Mutation, NCI Thesaurus)

This agent also induces antioxidant enzymes through AMP-activated protein kinase (AMPK) activation, inhibits NF-kB activation and decreases inflammation response, thereby sensitizing tumors to chemotherapy.

(Crystalline Genistein Formulation AXP107-11, NCI Thesaurus)

A synthetic analogue of camptothecin with potential antineoplastic and radio-sensitizing activities.

(Camptothecin Analogue TLC388, NCI Thesaurus)