REPLICATION

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 Dictionary entry overview: What does replication mean? 

• REPLICATION (noun)
  The noun REPLICATION has 7 senses:

1. the act of making copies

2. (genetics) the process whereby DNA makes a copy of itself before cell division

3. a quick reply to a question or remark (especially a witty or critical one)

4. (law) a pleading made by a plaintiff in reply to the defendant's plea or answer

5. the repetition of a sound resulting from reflection of the sound waves

6. copy that is not the original; something that has been copied

7. the repetition of an experiment in order to test the validity of its conclusion

  Familiarity information: REPLICATION used as a noun is common.

 Dictionary entry details 

• REPLICATION (noun)

Sense 1

Meaning:

The act of making copies

Classified under:

Nouns denoting acts or actions

Synonyms:

replication; reproduction

Context example:

Gutenberg's reproduction of holy texts was far more efficient

Hypernyms ("replication" is a kind of...):

copying (an act of copying)

Hyponyms (each of the following is a kind of "replication"):

scanning (the act of systematically moving a finely focused beam of light or electrons over a surface in order to produce an image of it for analysis or transmission)

sound reproduction (the reproduction of sound)

Sense 2

Meaning:

(genetics) the process whereby DNA makes a copy of itself before cell division

Classified under:

Nouns denoting natural processes

Hypernyms ("replication" is a kind of...):

biological process; organic process (a process occurring in living organisms)

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

Derivation:

replicate (reproduce or make an exact copy of)

Sense 3

Meaning:

A quick reply to a question or remark (especially a witty or critical one)

Classified under:

Nouns denoting communicative processes and contents

Synonyms:

comeback; counter; rejoinder; replication; retort; return; riposte

Context example:

it brought a sharp rejoinder from the teacher

Hypernyms ("replication" is a kind of...):

reply; response (the speech act of continuing a conversational exchange)

Hyponyms (each of the following is a kind of "replication"):

back talk; backtalk; lip; mouth; sass; sassing (an impudent or insolent rejoinder)

Sense 4

Meaning:

(law) a pleading made by a plaintiff in reply to the defendant's plea or answer

Classified under:

Nouns denoting communicative processes and contents

Hypernyms ("replication" is a kind of...):

pleading ((law) a statement in legal and logical form stating something on behalf of a party to a legal proceeding)

Domain category:

jurisprudence; law (the collection of rules imposed by authority)

Sense 5

Meaning:

The repetition of a sound resulting from reflection of the sound waves

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

echo; replication; reverberation; sound reflection

Context example:

she could hear echoes of her own footsteps

Hypernyms ("replication" is a kind of...):

reflection; reflectivity; reflexion (the ability to reflect beams or rays)

Hyponyms (each of the following is a kind of "replication"):

re-echo (the echo of an echo)

Sense 6

Meaning:

Copy that is not the original; something that has been copied

Classified under:

Nouns denoting man-made objects

Synonyms:

replica; replication; reproduction

Hypernyms ("replication" is a kind of...):

copy (a thing made to be similar or identical to another thing)

Hyponyms (each of the following is a kind of "replication"):

toy (a nonfunctional replica of something else (frequently used as a modifier))

Sense 7

Meaning:

The repetition of an experiment in order to test the validity of its conclusion

Classified under:

Nouns denoting acts or actions

Context example:

scientists will not believe an experimental result until they have seen at least one replication

Hypernyms ("replication" is a kind of...):

repeating; repetition (the act of doing or performing again)

Derivation:

replicate (make or do or perform again)

 Context examples 

Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in inhibition of DNA replication and repair and cell death in sensitive bacterial species.

(Moxifloxacin, NCI Thesaurus)

If the cell does not repair the damage so that normal DNA replication can take place, cancer could result.

(Using Electronic Cigarettes Can Damage DNA, The Titi Tudorancea Bulletin)

MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells.

(Mismatch Repair Pathway, NCI Thesaurus/KEGG)

Acodazole intercalates into DNA, resulting in disruption of DNA replication.

(Acodazole, NCI Thesaurus)

By blocking DNA synthesis and replication, cancer cells are unable to proliferate.

(Mercaptopurine Oral Suspension, NCI Thesaurus)

This results in the blockage of viral HCV RNA production and thus viral replication.

(Mericitabine, NCI Thesaurus)

As many of the simpler alterations to DNA may be repaired, such changes are only heritable once the change is fixed in the DNA by the process of replication.

(Mutation, NCI Thesaurus)

This results in cell lysis and prevents viral replication and the development of CMV disease.

(Multi-peptide CMV-Modified Vaccinia Ankara Vaccine, NCI Thesaurus)

Neuraminidase, which is not currently the main target antigen in traditional flu vaccines, enables newly formed flu viruses to exit the host cell and cause further viral replication in the body.

(Study finds factors that may influence influenza vaccine effectiveness, NIH)

This allele, which encodes E3 ubiquitin-protein ligase NEDD4 protein, may be involved in viral replication progression.

(NEDD4 wt Allele, NCI Thesaurus)