RAF

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does RAF mean? 

• RAF (noun)
  The noun RAF has 2 senses:

1. the airforce of Great Britain

2. a Marxist and Maoist terrorist organization in Germany; a network of underground guerillas who committed acts of violence in the service of the class struggle; a successor to the Baader-Meinhof Gang; became one of Europe's most feared terrorist groups; disbanded in 1998

  Familiarity information: RAF used as a noun is rare.

 Dictionary entry details 

• RAF (noun)

Sense 1

Meaning:

The airforce of Great Britain

Classified under:

Nouns denoting groupings of people or objects

Synonyms:

RAF; Royal Air Force

Hypernyms ("RAF" is a kind of...):

air force; airforce (the airborne branch of a country's armed forces)

Sense 2

Meaning:

A Marxist and Maoist terrorist organization in Germany; a network of underground guerillas who committed acts of violence in the service of the class struggle; a successor to the Baader-Meinhof Gang; became one of Europe's most feared terrorist groups; disbanded in 1998

Classified under:

Nouns denoting groupings of people or objects

Synonyms:

RAF; Red Army Faction

Instance hypernyms:

foreign terrorist organization; FTO; terrorist group; terrorist organization (a political movement that uses terror as a weapon to achieve its goals)

Domain category:

act of terrorism; terrorism; terrorist act (the calculated use of violence (or the threat of violence) against civilians in order to attain goals that are political or religious or ideological in nature; this is done through intimidation or coercion or instilling fear)

Domain region:

Deutschland; Federal Republic of Germany; FRG; Germany (a republic in central Europe; split into East Germany and West Germany after World War II and reunited in 1990)

 Context examples 

One component of IGF-1 mitogenic signaling is association of the receptor tyrosine kinase with Shc, Grb2, and Sos-1 to activate ras and the Map kinase cascade (raf, Mek, Erk).

(IGF-1 Signaling Pathway, NCI Thesaurus/BIOCARTA)

A potent inhibitor of the RAS/RAF/MAPK signaling pathway with potential antineoplastic activity.

(Diazepinomicin, NCI Thesaurus)

An orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity.

(Dabrafenib, NCI Thesaurus)

It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.

(Connector Enhancer of KSR-Like Protein, NCI Thesaurus)

A third pathway involves interaction of raf with mitochondria in response to IGF-1R activation.

(IGF1R Antiapoptosis Pathway, NCI Thesaurus/BIOCARTA)

This protein is comprised of half of the N-terminus of the putative UPF0606 protein KIAA1549 fused to the C-terminal half of the serine/threonine-protein kinase B-raf protein.

(KIAA1549/BRAF Fusion Protein, NCI Thesaurus)

Upon administration, pan-RAF kinase inhibitor MLN2480 inhibits Raf-mediated signal transduction pathways, which may lead to an inhibition of tumor cell growth.

(pan-RAF Kinase Inhibitor MLN2480, NCI Thesaurus)

This stabilization is dependent on the RAS/RAF/MAPK pathway, which appears to inhibit the proteasome-dependent degradation of MYC.

(p21 H-Ras Protein, NCI Thesaurus)

Mitogen-stimulated RAS stabilizes MYC protein and enhances MYC accumulation by the RAS/RAF/MAPK pathway, which appears to inhibit the proteasome-dependent degradation of MYC.

(Oncogene K-Ras, NCI Thesaurus)

The Map kinase cascade includes raf, Mek and Erk.

(Nerve Growth Factor Pathway, NCI Thesaurus/BIOCARTA)