PSA

Pronunciation (US):

(GB):

 Dictionary entry overview: What does PSA mean? 

• PSA (noun)
  The noun PSA has 1 sense:

1. a protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer

  Familiarity information: PSA used as a noun is very rare.

 Dictionary entry details 

• PSA (noun)

Sense 1

Meaning:

A protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer

Classified under:

Nouns denoting substances

Synonyms:

prostate specific antigen; PSA

Hypernyms ("PSA" is a kind of...):

protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)

 Context examples 

It is compared with the amount of PSA in the blood that is attached to other proteins.

(free PSA, NCI Dictionary)

A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA) and TRICOM, a combination of three immunostimulants (i.e., B7.1, ICAM-1, and LFA-3).

(Fowlpox-PSA-TRICOM Vaccine, NCI Thesaurus)

PSA, PSMA, PAP and MUC1 are frequently upregulated in prostate cancer cells; their expression in prostate cancer has been correlated with disease progression.

(mRNA-derived Prostate Cancer Vaccine CV9104, NCI Thesaurus)

Expression of glandular kallikrein, like PSA, seems to be restricted to the prostate.

(Human Glandular Kallikrein, NCI Thesaurus)

This complex is hydrolyzed by the enzyme prostate-specific antigen (PSA), resulting in the formation of doxorubicin and leucine-doxorubicin.

(L-377,202, NCI Thesaurus)

This agent may induce host T-cell responses against tumor cells expressing PSA.

(Mycobacterium w, NCI Thesaurus)

PSA, PSMA, PSCA and STEAP may be upregulated in prostate cancer cells; their expression in prostate cancer has been correlated with disease progression.

(mRNA-Derived Prostate Cancer Vaccine CV9103, NCI Thesaurus)

In addition, by reducing PTH levels, cinacalcet may reduce PSA levels; PTH appears to raise PSA levels and may increase prostate cancer cell growth.

(Cinacalcet Hydrochloride, NCI Thesaurus)

With benign prostate conditions, there is more free PSA, while cancer produces more of the attached form.

(Percent Free Prostate-Specific Antigen, NCI Thesaurus)

A recombinant human prostate-specific antigen (PSA) protein expressed by baculovirus.

(Baculovirus-Derived PSA Protein Vaccine, NCI Thesaurus)