PROTEOLYTIC ENZYME

Pronunciation (US):

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 Dictionary entry overview: What does proteolytic enzyme mean? 

• PROTEOLYTIC ENZYME (noun)
  The noun PROTEOLYTIC ENZYME has 1 sense:

1. any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis

  Familiarity information: PROTEOLYTIC ENZYME used as a noun is very rare.

 Dictionary entry details 

• PROTEOLYTIC ENZYME (noun)

Sense 1

Meaning:

Any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis

Classified under:

Nouns denoting substances

Synonyms:

peptidase; protease; proteinase; proteolytic enzyme

Hypernyms ("proteolytic enzyme" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "proteolytic enzyme"):

caspase (any of a group of proteases that mediate apoptosis)

ACE; angiotensin-converting enzyme; angiotensin converting enzyme (proteolytic enzyme that converts angiotensin I into angiotensin II)

plasminogen activator; urokinase (protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis)

renin (a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure)

 Context examples 

They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes.

(Bone Morphogenetic Protein, NLM, Medical Subject Headings)

Pancreatic proteolytic enzymes include trypsin, chymotrypsin and carboxypeptidase; these enzymes are secreted as zymogens, inactive precursors of the enzymes, and are activated in the lumen of the digestive canal.

(Pancreatic Proteolytic Enzymes, NCI Thesaurus)

A proteolytic enzyme that uses a metal ion, usually zinc, to catalyze the hydrolysis of peptide bonds.

(Metalloproteinase, NCI Thesaurus)

A proteolytic enzyme obtained from the pineapple plant that cleaves sulfhydryl groups.

(Bromelains, NCI Thesaurus)

A proteolytic enzyme and defibrinogenating agent derived from the venom of the Malayan pit viper, with profibrinolytic and anticoagulant activities.

(Ancrod, NCI Thesaurus)

A gene that encodes a proteolytic enzyme that depends on a metal ion to catalyze peptide bond hydrolysis.

(Metalloproteinase Gene, NCI Thesaurus)

Bone Morphogenetic Protein Receptor Genes encode Bone Morphogenetic Protein Receptors, activated by Bone Morphogenetic Proteins, non-collagenous bone-growth regulatory factors synthesized as large precursor molecules that are cleaved by proteolytic enzymes and form an active homodimer or heterodimer of two related bone morphogenetic proteins that stimulate osteogenesis.

(Bone Morphogenetic Protein Receptor Gene, NCI Thesaurus)

Encoded by Bone Morphogenetic Protein Genes (TGF Beta Superfamily), 9 structurally related Bone Morphogenetic Proteins are non-collagenous bone-growth regulatory factors synthesized as large precursor molecules that are cleaved by proteolytic enzymes and form an active homodimer or heterodimer of two related bone morphogenetic proteins that stimulate osteogenesis.

(Bone Morphogenetic Protein, NCI Thesaurus)

Bone Morphogenetic Protein Genes (TGF Beta Superfamily) encode 9 structurally related Bone Morphogenetic Proteins, non-collagenous bone-growth regulatory factors synthesized as large precursor molecules that are cleaved by proteolytic enzymes and form an active homodimer or heterodimer of two related bone morphogenetic proteins that stimulate osteogenesis.

(Bone Morphogenetic Protein Gene, NCI Thesaurus)

Another proteolytic enzyme, enteropeptidase, is associated with the brush border of enterocytes; this enzyme catalyses the conversion of trypsinogen into trypsin which, in turn, can activate a number of other pancreatic zymogens.

(Pancreatic Proteolytic Enzymes, NCI Thesaurus)