PROLINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does proline mean? 

• PROLINE (noun)
  The noun PROLINE has 1 sense:

1. an amino acid that is found in many proteins (especially collagen)

  Familiarity information: PROLINE used as a noun is very rare.

 Dictionary entry details 

• PROLINE (noun)

Sense 1

Meaning:

An amino acid that is found in many proteins (especially collagen)

Classified under:

Nouns denoting substances

Hypernyms ("proline" is a kind of...):

amino acid; aminoalkanoic acid (organic compounds containing an amino group and a carboxylic acid group)

 Context examples 

Proline is found in cartilage and is important for maintaining youthful skin as well as repair of muscle, connective tissue and skin damage.

(DL-Proline, NCI Thesaurus)

A keto derivative of the amino acid proline.

(Pidolic Acid, NCI Thesaurus)

This allele, which encodes proline-, glutamic acid- and leucine-rich protein 1, plays a role in the modulation of steroid receptor-mediated transcription.

(PELP1 wt Allele, NCI Thesaurus)

Collagen is differentiated from other fibrous proteins by its content of proline, hydroxyproline, and hydroxylysine; by its absence of tryptophan; and by its high content of polar groups.

(Collagen Gene, NCI Thesaurus)

Proline-, glutamic acid-, leucine-rich protein 1 (Pelp1 or modulator of nongenomic activity of estrogen, MNAR) is a recently discovered transmitter of estrogen signals.

(Pelp1 Estrogen Receptor Pathway, NCI Thesaurus/BIOCARTA)

Proline is first converted to a Schiff base and then converted by hydrolysis to glutamate-5-semialdehyde.

(Arginine, Histidine, Glutamate, Glutamine, and Proline Degradation Pathway, NCI Thesaurus/BIOCARTA)

A sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity.

(Captopril, NCI Thesaurus)

The proline linker facilitates the synthesis of a predominant (90%) positional isomer which allows for further increases in stability and a longer half-life than previous PEG conjugates.

(PEG-Proline-Interferon Alfa-2b, NCI Thesaurus)

In lispro insulin, the amino acid proline at B-28 and the amino acid lysine at B-29 are reversed, resulting in the rapid dissolution of this insulin to a monomer that is absorbed rapidly after subcutaneous administration.

(Insulin Lispro, NCI Thesaurus)

Expressed in a variety of cell types by human MLLT4 Gene, 1816-aa 206-kDa AF-6 Protein is a possible signal transduction protein controlled by Ras signaling pathways that is strongly similar to afadin (rat) and contains short stretches rich in proline, charged amino acids, serines, or glutamines, 1 dilute domain, 1 FHA domain, 1 PDZ/DHR domain, and 2 RAS-associating domains.

(AF-6 Protein, NCI Thesaurus)