OXYGENASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does oxygenase mean? 

• OXYGENASE (noun)
  The noun OXYGENASE has 1 sense:

1. an oxidoreductase that catalyzes the incorporation of molecular oxygen

  Familiarity information: OXYGENASE used as a noun is very rare.

 Dictionary entry details 

• OXYGENASE (noun)

Sense 1

Meaning:

An oxidoreductase that catalyzes the incorporation of molecular oxygen

Classified under:

Nouns denoting substances

Hypernyms ("oxygenase" is a kind of...):

oxidoreductase (an enzyme that catalyzes oxidation-reduction)

 Context examples 

The cytochrome P450 (CYP450) mono-oxygenase family of enzymes catalyzes the majority of the phase I reactions.

(Phase I Enzymes Inhibitor, NCI Thesaurus)

Certain allelic variants of the HMOX1 gene are associated with heme oxygenase 1 deficiency.

(HMOX1 wt Allele, NCI Thesaurus)

The anti-inflammatory actions of IL-10 appear to require induction of the enzyme heme oxygenase-1 (HO-1) through a map kinase pathway involving the p38 kinases.

(IL10 Anti-inflammatory Signaling Pathway, NCI Thesaurus/BIOCARTA)

Heme oxygenase 1 (288 aa, ~33 kDa) is encoded by the human HMOX1 gene.

(Heme Oxygenase 1, NCI Thesaurus)

Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors.

(Meloxicam, NCI Thesaurus)

Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.

(Celecoxib, NCI Thesaurus)

Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

(Naproxen, NCI Thesaurus)

Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

(Ketoprofen, NCI Thesaurus)

In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).

(Caffeic Acid Phenethyl Ester, NCI Thesaurus)

Cyclo-oxygenase inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).

(Cyclooxygenase inhibitor, NCI Dictionary)