English Dictionary

MONOVALENT

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 Dictionary entry overview: What does monovalent mean? 

MONOVALENT (adjective)
  The adjective MONOVALENT has 2 senses:

1. containing only one kind of antibodyplay

2. having a valence of 1play

  Familiarity information: MONOVALENT used as an adjective is rare.


 Dictionary entry details 


MONOVALENT (adjective)


Sense 1

Meaning:

Containing only one kind of antibody

Attribute:

valence; valency ((biology) a relative capacity to unite or react or interact as with antigens or a biological substrate)

Domain category:

immunology (the branch of medical science that studies the body's immune system)

Antonym:

polyvalent (containing several antibodies each capable of counteracting a specific antigen)


Sense 2

Meaning:

Having a valence of 1

Synonyms:

monovalent; univalent

Attribute:

valence; valency ((chemistry) a property of atoms or radicals; their combining power given in terms of the number of hydrogen atoms (or the equivalent))

Domain category:

chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)

Antonym:

polyvalent (having more than one valence, or having a valence of 3 or higher)


 Context examples 


A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 96.5, raised against an epitope from human melanoma-associated cell surface marker p97.

(Monoclonal Antibody 96.5 F(ab), NCI Thesaurus)

A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 8.2 raised against human melanoma-associated cell surface marker p97.

(Monoclonal Antibody 8.2 F(ab), NCI Thesaurus)

A monovalent vaccine containing hemagglutinin (HA) of influenza A (H1N1)-like virus with potential immunomodulating activity.

(Non-Adjuvanted A(H1N1) Influenza Vaccine, NCI Thesaurus)

A humanized monovalent monoclonal antibody directed against the hepatocyte growth factor receptor (c-Met) with potential antineoplastic activity.

(Onartuzumab, NCI Thesaurus)

The monovalent group -OH in such compounds as bases and some acids and alcohols.

(Hydroxyl Group, NCI Thesaurus)

The citrate salt of lithium, a monovalent cation with antimanic activity.

(Lithium Citrate, NCI Thesaurus)

A monovalent cation that is metabolized much like sodium and is important in many cellular functions inside or on the surface of cells.

(Lithium Cation, NCI Thesaurus)

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities.

(Iodine I 131-Labeled Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2, NCI Thesaurus)

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten.

(Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2, NCI Thesaurus)

A chemical group containing the monovalent -N=C=S group.

(Isothiocyanate, NCI Thesaurus)



 Learn English with... Proverbs 
"Sticks and stones may break my bones but words will never hurt me." (English proverb)

"We do not inherit the world from our ancestors; we borrow it from our children." (Native American proverb, tribe unknown)

"Seek counsel of him who makes you weep, and not of him who makes you laugh." (Arabic proverb)

"Gentle doctors cause smelly wounds." (Dutch proverb)



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