MODIFICATION

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 Dictionary entry overview: What does modification mean? 

• MODIFICATION (noun)
  The noun MODIFICATION has 4 senses:

1. the act of making something different (as e.g. the size of a garment)

2. slightly modified copy; not an exact copy

3. the grammatical relation that exists when a word qualifies the meaning of the phrase

4. an event that occurs when something passes from one state or phase to another

  Familiarity information: MODIFICATION used as a noun is uncommon.

 Dictionary entry details 

• MODIFICATION (noun)

Sense 1

Meaning:

The act of making something different (as e.g. the size of a garment)

Classified under:

Nouns denoting acts or actions

Synonyms:

adjustment; alteration; modification

Hypernyms ("modification" is a kind of...):

change (the action of changing something)

Hyponyms (each of the following is a kind of "modification"):

tightening (the act of making something tighter)

accommodation ((physiology) the automatic adjustment in focal length of the natural lens of the eye)

adaptation ((physiology) the responsive adjustment of a sense organ (as the eye) to varying conditions (as of light))

tune (the adjustment of a radio receiver or other circuit to a required frequency)

laxation; loosening (the act of making something less tight)

Derivation:

modify (cause to change; make different; cause a transformation)

modify (make less severe or harsh or extreme)

Sense 2

Meaning:

Slightly modified copy; not an exact copy

Classified under:

Nouns denoting man-made objects

Context example:

a modification of last year's model

Hypernyms ("modification" is a kind of...):

copy (a thing made to be similar or identical to another thing)

Derivation:

modify (make less severe or harsh or extreme)

Sense 3

Meaning:

The grammatical relation that exists when a word qualifies the meaning of the phrase

Classified under:

Nouns denoting relations between people or things or ideas

Synonyms:

limiting; modification; qualifying

Hypernyms ("modification" is a kind of...):

grammatical relation (a linguistic relation established by grammar)

Hyponyms (each of the following is a kind of "modification"):

restrictiveness (a grammatical qualification that makes the meaning more specific ('red hat' has a more specific meaning than 'hat'))

apposition (a grammatical relation between a word and a noun phrase that follows)

Derivation:

modify (add a modifier to a constituent)

Sense 4

Meaning:

An event that occurs when something passes from one state or phase to another

Classified under:

Nouns denoting natural events

Synonyms:

alteration; change; modification

Context example:

the neighborhood had undergone few modifications since his last visit years ago

Hypernyms ("modification" is a kind of...):

happening; natural event; occurrence; occurrent (an event that happens)

Hyponyms (each of the following is a kind of "modification"):

increase (a change resulting in an increase)

decrease; drop-off; lessening (a change downward)

easing; moderation; relief (a change for the better)

deformation (alteration in the shape or dimensions of an object as a result of the application of stress to it)

transition (a change from one place or state or subject or stage to another)

shift; transformation; transmutation (a qualitative change)

scintillation; sparkling; twinkle (a rapid change in brightness; a brief spark or flash)

play; shimmer (a weak and tremulous light)

transmutation ((physics) the change of one chemical element into another (as by nuclear decay or radioactive bombardment))

damage; harm; impairment (the occurrence of a change for the worse)

development (a recent event that has some relevance for the present situation)

revolution (a drastic and far-reaching change in ways of thinking and behaving)

chromosomal mutation; genetic mutation; mutation ((genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism)

sex change (a change in a person's physical sexual characteristics (as by surgery and hormone treatments))

loss of consciousness (the occurrence of a loss of the ability to perceive and respond)

destabilization (an event that causes a loss of equilibrium (as of a ship or aircraft))

death; decease; expiry (the event of dying or departure from life)

conversion (a change of religion)

fluctuation; variation (an instance of change; the rate or magnitude of change)

vagary (an unexpected and inexplicable change in something (in a situation or a person's behavior, etc.))

breakup; detachment; separation (coming apart)

birth; nascence; nascency; nativity (the event of being born)

surprise (a sudden unexpected event)

sublimation ((psychology) modifying the natural expression of an impulse or instinct (especially a sexual one) to one that is socially acceptable)

mutation (a change or alteration in form or qualities)

break (an abrupt change in the tone or register of the voice (as at puberty or due to emotion))

avulsion (an abrupt change in the course of a stream that forms the boundary between two parcels of land resulting in the loss of part of the land of one landowner and a consequent increase in the land of another)

deceleration; retardation; slowing (a decrease in rate of change)

acceleration (an increase in rate of change)

Derivation:

modify (make less severe or harsh or extreme)

 Context examples 

Modification of parkin and UCHL1 are associated with the ubiquitin-proteasome system pathway and may increase proteotoxic stress.

(Parkinson's Disease Pathway KEGG, NCI Thesaurus/KEGG)

Several forms of post-translational modification regulate protein activities.

(CARM1 Transcription Regulation Pathway, NCI Thesaurus/BIOCARTA)

Four main isoforms exist, including CD56, but many variants result from alternative splicing and post-translational modifications.

(CD56 Antigen, NCI Thesaurus)

Peptide Metabolism involves cellular biotransforming chemical modifications of peptides.

(Peptide Metabolism, NCI Thesaurus)

This allele, which encodes protein-arginine deiminase type-4 protein, plays a role in the post-translational protein modification.

(PADI4 wt Allele, NCI Thesaurus)

This protein plays a role in both B-cell functioning and DNA modification.

(Activation-Induced Cytidine Deaminase, NCI Thesaurus)

Modification of the core histones through phosphorylation regulates chromatin condensation.

(AKAP8 in Mitosis Pathway, NCI Thesaurus/BIOCARTA)

This protein plays a role in protein-protein interactions, protein modification and apoptosis induction.

(Apoptotic Protease-Activating Factor 1, NCI Thesaurus)

This gene plays a role in glycoprotein modification.

(B3GAT1 Gene, NCI Thesaurus)

Four main isoforms exist, including CD56 (ANTIGENS, CD56), but there are many other variants resulting from alternative splicing and post-translational modifications.

(CD56 Antigen, NLM, Medical Subject Headings)