MALIGNANCY

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 Dictionary entry overview: What does malignancy mean? 

• MALIGNANCY (noun)
  The noun MALIGNANCY has 2 senses:

1. (medicine) a malignant state; progressive and resistant to treatment and tending to cause death

2. quality of being disposed to evil; intense ill will

  Familiarity information: MALIGNANCY used as a noun is rare.

 Dictionary entry details 

• MALIGNANCY (noun)

Sense 1

Meaning:

(medicine) a malignant state; progressive and resistant to treatment and tending to cause death

Classified under:

Nouns denoting stable states of affairs

Synonyms:

malignance; malignancy

Hypernyms ("malignancy" is a kind of...):

disease (an impairment of health or a condition of abnormal functioning)

Meronyms (parts of "malignancy"):

cancer cell (a cell that is part of a malignant tumor)

Domain category:

medical specialty; medicine (the branches of medical science that deal with nonsurgical techniques)

Hyponyms (each of the following is a kind of "malignancy"):

malignant neoplasm; malignant tumor; metastatic tumor (a tumor that is malignant and tends to spread to other parts of the body)

Derivation:

malignant (dangerous to health; characterized by progressive and uncontrolled growth (especially of a tumor))

Sense 2

Meaning:

Quality of being disposed to evil; intense ill will

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

malignance; malignancy; malignity

Hypernyms ("malignancy" is a kind of...):

evil; evilness (the quality of being morally wrong in principle or practice)

Attribute:

malign (evil or harmful in nature or influence)

Antonym:

benignancy (the quality of being kind and gentle)

 Context examples 

An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies.

(Monoclonal Antibody A1G4 Anti-Idiotype Vaccine, NCI Thesaurus)

Overexpression of EGFR, a tyrosine kinase, and its upregulated activity have been implicated in the pathogeneses of several malignancies.

(Monoclonal Antibody RG 83852, NCI Thesaurus)

Monoclonal antibody 3A1 is used to diagnose and classify T cell malignancies.

(Monoclonal Antibody 3A1, NCI Thesaurus)

A neoplasm composed of an epithelial component and/or a mesenchymal component, for which the malignancy status has not been established.

(Mixed Neoplasm, NCI Thesaurus/CDISC)

Virus infections are associated with malignancies and some other diseases such as wasting, and osteopetrosis.

(Alpharetrovirus, NCI Thesaurus)

Metastasis is characteristic of advanced malignancies, but in rare instances can be seen in neoplasms lacking malignant morphology.

(Metastatic Neoplasm, NCI Thesaurus)

A murine monoclonal antibody (MoAb) with application in Immunotherapy and radioimmunodetection in T-cell malignancies.

(Monoclonal Antibody T101, NCI Thesaurus)

Monoclonal antibody T101 may be used in the immunotherapy of T-cell malignancies.

(Monoclonal Antibody T101 F(ab)2, NCI Thesaurus)

Aberrant expression of the gene may be associated with corticotrophic malignancies and Cushing disease.

(NR2C2 wt Allele, NCI Thesaurus)

A neoplasm arising from tooth-forming tissues, for which the malignancy status has not been established.

(Odontogenic Neoplasm, NCI Thesaurus/CDISC)