LDL CHOLESTEROL

Pronunciation (US):

(GB):

 Dictionary entry overview: What does LDL cholesterol mean? 

• LDL CHOLESTEROL (noun)
  The noun LDL CHOLESTEROL has 1 sense:

1. the cholesterol in low-density lipoproteins; the 'bad' cholesterol; a high level in the blood is thought to be related to various pathogenic conditions

  Familiarity information: LDL CHOLESTEROL used as a noun is very rare.

 Dictionary entry details 

• LDL CHOLESTEROL (noun)

Sense 1

Meaning:

The cholesterol in low-density lipoproteins; the 'bad' cholesterol; a high level in the blood is thought to be related to various pathogenic conditions

Classified under:

Nouns denoting substances

Hypernyms ("LDL cholesterol" is a kind of...):

cholesterin; cholesterol (an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues)

Hyponyms (each of the following is a kind of "LDL cholesterol"):

oxidized LDL cholesterol (LDL cholesterol that has been bombarded by free radicals; it is thought to cause atherosclerosis)

Holonyms ("LDL cholesterol" is a substance of...):

beta-lipoprotein; LDL; low-density lipoprotein (a lipoprotein that transports cholesterol in the blood; composed of moderate amount of protein and a large amount of cholesterol; high levels are thought to be associated with increased risk of coronary heart disease and atherosclerosis)

 Context examples 

These participants had 39% lower triglyceride levels, 22% higher HDL choles­terol levels, 16% lower LDL cholesterol levels, and 46% lower circulating APOC3 levels compared to participants who did not have any of these genetic misspellings.

(Rare mutations reduce heart disease risk, NIH)

Eprotirome reduces serum LDL cholesterol levels by increasing hepatic clearance due to increased expression of the hepatic LDL-receptor gene, and also reduces the serum level of Lp(a) lipoprotein.

(Eprotirome, NCI Thesaurus)

The low-glycemic index/low-carbohydrate diet resulted in similar insulin sensitivity, systolic blood pressure and HDL and LDL cholesterol levels when compared to the high-glycemic index/high-carbohydrate diet.

(Low-glycemic diets may not improve cardiovascular outcomes when compared to high-glycemic diets, NIH)

Ethyl icosapentate reduces serum triglycerides without an increase in LDL cholesterol, but increases the cholesterol and triglyceride content in skeletal muscle.

(Ethyl Icosapentate, NCI Thesaurus)

Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood.

(Ezetimibe, NCI Thesaurus)

A relative measurement (ratio or percentage) of the amount of HDL cholesterol compared to LDL cholesterol in a biological specimen.

(HDL Cholesterol to LDL Cholesterol Ratio Measurement, NCI Thesaurus/CDISC)

This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes.

(Metformin, NCI Thesaurus)

An antilipidemic agent derived from fibric acid that lowers serum LDL cholesterol levels by activating peroxisome proliferator activated receptor alpha (PPARa).

(Fibrate Antilipidemic Agent, NCI Thesaurus)

In Phase II trials canosimibe reduced LDL cholesterol levels, but it did not demonstrate the desired efficacy in a Phase III study, and was discontinued.

(Canosimibe, NCI Thesaurus)

In their study, they found that pistachios lowered LDL cholesterol by 6 percent but didn’t significantly change total plasma cholesterol.

(Going Nuts Over Calories, U.S. Department of Agriculture)