KNOCKOUT

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does knockout mean? 

• KNOCKOUT (noun)
  The noun KNOCKOUT has 2 senses:

1. a very attractive or seductive looking woman

2. a blow that renders the opponent unconscious

  Familiarity information: KNOCKOUT used as a noun is rare.

• KNOCKOUT (adjective)
  The adjective KNOCKOUT has 1 sense:

1. very strong or vigorous

  Familiarity information: KNOCKOUT used as an adjective is very rare.

 Dictionary entry details 

• KNOCKOUT (noun)

Sense 1

Meaning:

A very attractive or seductive looking woman

Classified under:

Nouns denoting people

Synonyms:

beauty; dish; knockout; looker; lulu; mantrap; peach; ravisher; smasher; stunner; sweetheart

Hypernyms ("knockout" is a kind of...):

adult female; woman (an adult female person (as opposed to a man))

Sense 2

Meaning:

A blow that renders the opponent unconscious

Classified under:

Nouns denoting acts or actions

Synonyms:

kayo; knockout; KO

Hypernyms ("knockout" is a kind of...):

blow (a powerful stroke with the fist or a weapon)

Hyponyms (each of the following is a kind of "knockout"):

technical knockout; TKO (a knockout declared by the referee who judges one boxer unable to continue)

Derivation:

knock out (knock unconscious or senseless)

• KNOCKOUT (adjective)

Sense 1

Meaning:

Very strong or vigorous

Synonyms:

hard; knockout; severe

Context example:

a severe blow

Similar:

strong (having strength or power greater than average or expected)

 Context examples 

The importance of JAK3 in IL-7 signaling is supported by the similarity of the immune defects in JAK3 knockout mice and IL-7 knockout mice.

(IL7 Signaling Pathway, NCI Thesaurus/BIOCARTA)

Knockouts are often created in laboratory organisms such as yeast or mice so that scientists can study the knockout organism as a model for a particular disease.

(Knock-out, NCI Thesaurus)

On the contrary, all the URI knockout mice died from gastrointestinal syndrome.

(New Way Discovered for Protecting against High-Dose Radiation Damage, The Titi Tudorancea Bulletin)

Models of human disease produced through gene knockout methods

(Gene Knock-Out Model, NCI Thesaurus)

They guessed that these double-knockout mice would have the same or worse heart problems as the mice without GR.

(Healthy hearts need two proteins working together, National Institutes of Health)

The Animal Models Service Shared Resource is primarily dedicated to the production, development and characterization of biomedical relevant animal models and species for cancer research including transgenic, knockout, mutant, etc. experimental animal lines.

(Animal Models Service Shared Resource, NCI Thesaurus)

Studies with homozygous knockout mice have suggested that stem cell factor (SCF or KITLG), c-Kit, microphthalmia (Mitf), and B-cell CLL/lymphoma 2 (Bcl2) genes regulate melanocytic development.

(Melanocyte Development Pathway, NCI Thesaurus/BIOCARTA)

Knockout mice are used as animal models for various diseases, such as cystic fibrosis, and are helping to clarify the functions of the genes studied within the fields of immunology, cancer genetics, and developmental biology.

(Knock-Out Mouse, NLM, Medical Subject Headings)