INTERCALATE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does intercalate mean? 

• INTERCALATE (verb)
  The verb INTERCALATE has 1 sense:

1. insert (days) in a calendar

  Familiarity information: INTERCALATE used as a verb is very rare.

 Dictionary entry details 

• INTERCALATE (verb)

Present simple: I / you / we / they intercalate    ... he / she / it intercalates   
Past simple: intercalated   
Past participle: intercalated   
-ing form: intercalating   

Sense 1

Meaning:

Insert (days) in a calendar

Classified under:

Verbs of size, temperature change, intensifying, etc.

Hypernyms (to "intercalate" is one way to...):

add (make an addition (to); join or combine or unite with others; increase the quality, quantity, size or scope of)

Sentence frame:

Somebody ----s something

 Context examples 

Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, as well as RNA and protein synthesis.

(Berubicin, NCI Thesaurus)

Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis.

(Berubicin Hydrochloride, NCI Thesaurus)

Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.

(Mitoxantrone, NCI Thesaurus)

Banoxantrone intercalates into and crosslinks DNA, and inhibits topoisomerase II.

(Banoxantrone, NCI Thesaurus)

These agents also intercalate into DNA, leading to cell cycle arrest in the G1 phase and inhibition of mitosis and terminal cell differentiation.

(Antineoplaston Agent, NCI Thesaurus)

Annamycin intercalates into DNA and inhibits topoisomerase II, resulting in the inhibition of DNA replication and repair and RNA and protein synthesis.

(Annamycin Liposomal, NCI Thesaurus)

A substance that is based on the structure of anthraquinone and inhibits topoisomerase-II by intercalating into the DNA double strand.

(Anthraquinone Analogue, NCI Thesaurus)

This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis.

(Antineoplaston A10, NCI Thesaurus)

Similar to doxorubicin, morpholinodoxorubicin intercalates into DNA and causes single- and double-strand breaks in DNA via inhibition of topoisomerase I and II.

(Morpholinodoxorubicin, NCI Thesaurus)

Upon intravenous administration, doxorubicin intercalates DNA, interferes with the activity of topoisomerase II, and causes DNA adducts and other DNA damage, resulting in tumor cell growth inhibition and apoptosis.

(Nanoparticle-encapsulated Doxorubicin Hydrochloride, NCI Thesaurus)