INOSINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does inosine mean? 

• INOSINE (noun)
  The noun INOSINE has 1 sense:

1. a nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar

  Familiarity information: INOSINE used as a noun is very rare.

 Dictionary entry details 

• INOSINE (noun)

Sense 1

Meaning:

A nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar

Classified under:

Nouns denoting substances

Hypernyms ("inosine" is a kind of...):

nucleoside (a glycoside formed by partial hydrolysis of a nucleic acid)

 Context examples 

Inhibition of inosine monophosphate dehydrogenase can lead to inhibition of cell proliferation.

(Inosine Monophosphate Dehydrogenase Inhibitor, NCI Thesaurus)

An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections.

(Inosine Pranobex, NLM, Medical Subject Headings)

Inosine-5'-monophosphate dehydrogenase 1 (514 aa, ~55 kDa) is encoded by the human IMPDH1 gene.

(Inosine-5'-Monophosphate Dehydrogenase 1, NCI Thesaurus)

Inosine-5'-monophosphate dehydrogenase 2 (514 aa, ~56 kDa) is encoded by the human IMPDH2 gene.

(Inosine-5'-Monophosphate Dehydrogenase 2, NCI Thesaurus)

This allele, which encodes inosine-5'-monophosphate dehydrogenase 1 protein, is involved in de novo synthesis of guanine nucleotides.

(IMPDH1 wt Allele, NCI Thesaurus)

Inosine dialdehyde inhibits ribonucleotide reductase, resulting in decreased synthesis of DNA, RNA, and proteins, and G2/M-phase cell cycle arrest.

(Inosine Dialdehyde, NCI Thesaurus)

Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells.

(Aminothiadiazole, NCI Thesaurus)

It is a type of inosine monophosphate dehydrogenase (IMPDH) inhibitor.

(AVN944, NCI Dictionary)

L-alanosine inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate, an intermediate in purine metabolism.

(Alanosine, NCI Thesaurus)

As an immunosuppressive agent in vivo, the active metabolite mycophenolate reversibly inhibits inosine 5'-monophosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanine nucleotides, thereby retarding T-cell and B-cell proliferation.

(Mycophenolate, NCI Thesaurus)