IMPLICATED

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does implicated mean? 

• IMPLICATED (adjective)
  The adjective IMPLICATED has 1 sense:

1. culpably involved

  Familiarity information: IMPLICATED used as an adjective is very rare.

 Dictionary entry details 

• IMPLICATED (adjective)

Sense 1

Meaning:

Culpably involved

Synonyms:

concerned; implicated

Context example:

an innocent person implicated by circumstances in a crime

Similar:

involved (connected by participation or association or use)

 Context examples 

The gene has also been implicated in the pathogenesis of Alzheimer's disease.

(APPBP2 Gene, NCI Thesaurus)

Inappropriate expression of ARID proteins is increasingly implicated in tumorigenesis.

(ARID Domain, NCI Thesaurus)

NCK2 SH3 domains bind proteins implicated in cytoskeletal regulation: CAP/ponsin, ABI1, dynamin, PAK1, HNRNPK, and axin.

(NCK Adaptor Protein 2, NCI Thesaurus)

Recent studies point to the ER as a third subcellular compartment implicated in apoptotic execution.

(Apoptosis Pathway, NCI Thesaurus/KEGG)

Implicated in control of feeding, energy balance, and secretion of GNRH, NPY may also regulate angiogenesis.

(Neuropeptide Y, NCI Thesaurus)

Implicated in a variety of human tumors, specific amino acid mutations activate c-RAS and transform cells.

(Oncogene N-RAS, NCI Thesaurus)

Presenilin-1 (PS1) is associated with gamma secretase activity that cleaves amyloid precursor protein (APP) and is implicated in Alzheimer's disease.

(Notch and Wnt Signaling Pathway, NCI Thesaurus/BIOCARTA)

IGF1/2 ligands stimulate cell proliferation, enable oncogenic transformation, and suppress apoptosis; IGF1/2 signaling has been highly implicated in tumorigenesis and metastasis.

(Anti-IGF1/2 Monoclonal Antibody MEDI-573, NCI Thesaurus)

BlyS, a member of TNF family supporting B-lymphocyte maturation and survival, has been implicated in the pathogenesis of autoimmune diseases and B-lymphocyte malignancies.

(Belimumab, NCI Thesaurus)

CLCA2 has been implicated as a tumor suppressor for breast cancer.

(Calcium-Activated Chloride Channel-2, NCI Thesaurus)