IMPLICATE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does implicate mean? 

• IMPLICATE (verb)
  The verb IMPLICATE has 2 senses:

1. bring into intimate and incriminating connection

2. impose, involve, or imply as a necessary accompaniment or result

  Familiarity information: IMPLICATE used as a verb is rare.

 Dictionary entry details 

• IMPLICATE (verb)

Present simple: I / you / we / they implicate    ... he / she / it implicates   
Past simple: implicated   
Past participle: implicated   
-ing form: implicating   

Sense 1

Meaning:

Bring into intimate and incriminating connection

Classified under:

Verbs of being, having, spatial relations

Context example:

He is implicated in the scheme to defraud the government

Hypernyms (to "implicate" is one way to...):

affect; involve; regard (connect closely and often incriminatingly)

Sentence frames:

Somebody ----s something
Somebody ----s somebody
Something ----s somebody
Something ----s something

Derivation:

implication (an accusation that brings into intimate and usually incriminating connection)

implication (a relation implicated by virtue of involvement or close connection (especially an incriminating involvement))

Sense 2

Meaning:

Impose, involve, or imply as a necessary accompaniment or result

Classified under:

Verbs of being, having, spatial relations

Synonyms:

entail; implicate

Context example:

What does this move entail?

Hypernyms (to "implicate" is one way to...):

lead (tend to or result in)

Sentence frame:

Something ----s something

Derivation:

implication (something that is inferred (deduced or entailed or implied))

implication (a meaning that is not expressly stated but can be inferred)

implication (a logical relation between propositions p and q of the form 'if p then q'; if p is true then q cannot be false)

 Context examples 

The wild-type function is currently unknown, however allelic variants have been implicated in several cancers.

(CEACAM5 wt Allele, NCI Thesaurus)

Mutations of the gene, which generates variant alleles have been implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, suggesting that it is a tumor suppressor candidate.

(CDKN1C wt Allele, NCI Thesaurus)

Methylation of the gene generates allelic variants that are implicated in the pathogenesis of several cancers.

(CCND2 wt Allele, NCI Thesaurus)

E-cadherin inactivation has been implicated in cancer development.

(Cell to Cell Adhesion Signaling Pathway, NCI Thesaurus/BIOCARTA)

Beside a steroidal platform, critical features implicated in the pharmacophore include a set of covalently linked polar and nonpolar domains and the spiroketals.

(Cephalostatin, NCI Thesaurus)

Kinin peptides are implicated in many physiological and pathological processes including the regulation of blood pressure and sodium homeostasis, inflammatory processes, and the cardioprotective effects of preconditioning.

(Complement and Coagulation Cascade, NCI Thesaurus/KEGG)

This allele, which encodes chloride channel protein, may play a role in cellular adhesion and has also been implicated as a tumor suppressor gene for breast cancer.

(CLCA2 wt Allele, NCI Thesaurus)

This gene plays a role in the transfer of cholesteryl esters between lipoproteins and has been implicated in atherosclerosis susceptibility.

(CETP Gene, NCI Thesaurus)

This allele, which encodes small inducible cytokine A7 protein, is involved in macrophage chemoattraction during inflammation and variants of the allele have been implicated in metastasis.

(CCL7 wt Allele, NCI Thesaurus)

Variant alleles have been implicated in chemokine effects relating to the development and growth of vascular tumors.

(CCBP2 wt Allele, NCI Thesaurus)