IMMUNOGLOBULIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does immunoglobulin mean? 

• IMMUNOGLOBULIN (noun)
  The noun IMMUNOGLOBULIN has 1 sense:

1. a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response

  Familiarity information: IMMUNOGLOBULIN used as a noun is very rare.

 Dictionary entry details 

• IMMUNOGLOBULIN (noun)

Sense 1

Meaning:

A class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response

Classified under:

Nouns denoting substances

Synonyms:

Ig; immune gamma globulin; immune globulin; immune serum globulin; immunoglobulin

Hypernyms ("immunoglobulin" is a kind of...):

gamma globulin; human gamma globulin (a plasma protein containing the immunoglobulins that are responsible for immune responses)

antibody (any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response)

Hyponyms (each of the following is a kind of "immunoglobulin"):

IgA; immunoglobulin A (one of the most common of the five major classes of immunoglobulins; the chief antibody in the membranes of the gastrointestinal and respiratory tracts)

IgD; immunoglobulin D (one of the five major classes of immunoglobulins; present in blood serum in small amounts)

IgE; immunoglobulin E (one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes)

IgG; immunoglobulin G (one of the five major classes of immunoglobulins; the main antibody defense against bacteria)

IgM; immunoglobulin M (one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G)

tetanus immune globulin; tetanus immunoglobulin (sterile solution of globulins derived from the blood plasma of a person who has been immunized for tetanus; provides short-term immunization against tetanus in cases of possible exposure to the tetanus bacillus)

 Context examples 

The heavy chain of the immunoglobulin, IgA, is defective.

(Multiple Myeloma-IgA, NCI Thesaurus)

This allele, which encodes high affinity immunoglobulin epsilon receptor subunit beta protein, plays a role in both immunoglobulin binding and mast cell responses.

(MS4A2 wt Allele, NCI Thesaurus)

If the B cell receptor immunoglobulin binds specific antigen, then the cell internalizes the antigen and presents it to T cells in MHC II, where it is recognized by the T cell receptor.

(Antigen Dependent B Cell Activation Pathway, NCI Thesaurus/BIOCARTA)

They are formed from parts of the variable regions of the Fab fragment of the immunoglobulin.

(Antibody Binding Site, NLM, Medical Subject Headings)

A recombinant immunoglobulin antibody directed against the tumor-associated carcinoembryonic antigen (CEA).

(Monoclonal Antibody COL-6, NCI Thesaurus)

Immunoglobulins raised xenogeneically against lymphocyte populations.

(Antilymphocyte Serum, NCI Thesaurus)

They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

(Murine B-Lymphocytes, NLM, Medical Subject Headings)

Containing only the antigen-binding fragment of an immunoglobulin molecule, an FAB (fragment antibody) offers the advantages of smaller size and lower cross-reactivity compared to complete antibodies.

(Monoclonal Antibody T101 F(ab)2, NCI Thesaurus)

A recombinant immunoglobulin antibody directed against the tumor-associated antigen carcinoembryonic antigen (CEA).

(Monoclonal Antibody COL-1, NCI Thesaurus)

A laboratory test result indicating the presence of an abnormally high level of monoclonal immunoglobulins in the blood or urine.

(Monoclonal Gammopathy, NCI Thesaurus)