HYPERSENSITIVITY REACTION

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 Dictionary entry overview: What does hypersensitivity reaction mean? 

• HYPERSENSITIVITY REACTION (noun)
  The noun HYPERSENSITIVITY REACTION has 1 sense:

1. an inappropriate and excessive reaction to an allergen (as pollen or dust or animal hair or certain foods); severity ranges from mild allergy to severe systemic reactions leading to anaphylactic shock

  Familiarity information: HYPERSENSITIVITY REACTION used as a noun is very rare.

 Dictionary entry details 

• HYPERSENSITIVITY REACTION (noun)

Sense 1

Meaning:

An inappropriate and excessive reaction to an allergen (as pollen or dust or animal hair or certain foods); severity ranges from mild allergy to severe systemic reactions leading to anaphylactic shock

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("hypersensitivity reaction" is a kind of...):

hypersensitivity (pathological sensitivity)

Hyponyms (each of the following is a kind of "hypersensitivity reaction"):

hives; nettle rash; urticaria; urtication (an itchy skin eruption characterized by weals with pale interiors and well-defined red margins; usually the result of an allergic response to insect bites or food or drugs)

allergic reaction; allergy (hypersensitivity reaction to a particular allergen; symptoms can vary greatly in intensity)

anaphylaxis (hypersensitivity reaction to the ingestion or injection of a substance (a protein or drug) resulting from prior contact with a substance)

allergic rhinitis (rhinitis caused by an allergic reaction)

 Context examples 

This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.

(Ketotifen, NCI Thesaurus)

Hypersensitivity reactions are less common with iron sucrose compared to other parenteral iron products, such as iron dextran.

(Iron Sucrose Injection, NCI Thesaurus)

Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.

(Immediate Hypersensitivity, NLM, Medical Subject Headings)

Lipooxygenase is involved in the metabolism of eicosanoids (such as prostaglandins and leukotrienes) and its inhibition can suppress hypersensitivity reactions.

(Lipooxygenase Inhibitor, NCI Thesaurus)

This liposomal formulation solubilizes docetaxel without the use of toxic solvents such as Tween 80, permitting the administration of larger doses of docetaxel while avoiding solvent-associated toxicity, including hypersensitivity reactions.

(Liposomal Docetaxel, NCI Thesaurus)

Upon administration to the eye, lodoxamide tromethamide inhibits type I immediate hypersensitivity reaction by preventing the antigen-stimulated calcium influx into mast cells, thereby inhibiting release of histamine.

(Lodoxamide Tromethamine, NCI Thesaurus)

Lodoxamide appears to inhibit the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell degranulation and the release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions.

(Lodoxamide, NCI Thesaurus)

It is considered by some to be a form of hypersensitivity reaction.

(Goodpasture Syndrome, NLM, Medical Subject Headings)

Immediate hypersensitivity reaction - type I reaction, involves immunoglobulin E (IgE)-mediated release of chemical mediators from mast cells and basophils.

(Immediate Hypersensitivity, NCI Thesaurus)

Conditions in which inhalation of organic dusts results in hypersensitivity reactions at the alveolar level, associated with the production of precipitins.

(Extrinsic Allergic Alveolitis, NLM, Medical Subject Headings)