HALLMARK

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 Dictionary entry overview: What does hallmark mean? 

• HALLMARK (noun)
  The noun HALLMARK has 2 senses:

1. a distinctive characteristic or attribute

2. a mark on an article of trade to indicate its origin and authenticity

  Familiarity information: HALLMARK used as a noun is rare.

 Dictionary entry details 

• HALLMARK (noun)

Sense 1

Meaning:

A distinctive characteristic or attribute

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

earmark; hallmark; stylemark; trademark

Hypernyms ("hallmark" is a kind of...):

characteristic (a distinguishing quality)

Hyponyms (each of the following is a kind of "hallmark"):

mold; mould (a distinctive nature, character, or type)

Sense 2

Meaning:

A mark on an article of trade to indicate its origin and authenticity

Classified under:

Nouns denoting communicative processes and contents

Synonyms:

assay-mark; authentication; hallmark

Hypernyms ("hallmark" is a kind of...):

mark; marker; marking (a distinguishing symbol)

 Context examples 

The hallmark of this disease is the selective death of motor neurons in the brain and spinal cord, leading to paralysis of voluntary muscles.

(Amyotrophic Lateral Sclerosis Pathway, NCI Thesaurus/KEGG)

Neither type of exercise prevented amyloid clumps — a hallmark of Alzheimer's disease — from continuing to develop in the brains of the 70 adults who participated in the study.

(Aerobic Exercise Slows Cognitive Decline in Adults at Risk of Alzheimer's, The Titi Tudorancea Bulletin)

In Alzheimer’s disease, beta-amyloid proteins clump together to form amyloid plaques, a hallmark of the disease.

(Lack of sleep may be linked to risk factor for Alzheimer’s disease, National Institutes of Health)

The hallmark pathological findings are progressive myocyte loss and fibrofatty replacement, with a predilection for the right ventricle.

(Arrhythmogenic Right Ventricular Cardiomyopathy Pathway, NCI Thesaurus/KEGG)

The strain is commonly used as a model for rheumatoid arthritis as it mimics hallmarks of the human disease when immunized with type II collagen.

(DBA/1 Mouse, NCI Thesaurus)

The amyloid-beta peptide (Ab), a proteolytic fragment of amyloid precursor protein (APP), is the major component of senile plaques, the hallmark of Alzheimer's disease.

(Platelet Amyloid Precursor Protein Pathway, NCI Thesaurus/BIOCARTA)

It is the hallmark for chronic myelogenous leukemia (CML).

(Philadelphia chromosome, NCI Thesaurus)

A histologic hallmark of this tumor is the 'specific glioneuronal element', characterized by columns, made up of bundles of axons, oriented perpendicularly to the cortical surface.

(Dysembryoplastic Neuroepithelial Tumor, NCI Thesaurus/Adapted from WHO)

These plaques, a hallmark of atherosclerosis (hardening of the arteries), also tended to be more structurally unstable, which means that they have an increased likelihood of causing heart attack and stroke.

(Researchers have found a link between allergen in red meat and heart disease, National Institutes of Health)

They hypothesize that such individuals might be at increased risk for alcohol use disorder or emotional dysfunction problems, which are hallmarks of chronic exposure to high levels of stress.

(Researchers identify brain circuits that help people cope with stress, NIH)