GENOTYPE

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 Dictionary entry overview: What does genotype mean? 

• GENOTYPE (noun)
  The noun GENOTYPE has 2 senses:

1. a group of organisms sharing a specific genetic constitution

2. the particular alleles at specified loci present in an organism

  Familiarity information: GENOTYPE used as a noun is rare.

 Dictionary entry details 

• GENOTYPE (noun)

Sense 1

Meaning:

A group of organisms sharing a specific genetic constitution

Classified under:

Nouns denoting groupings of people or objects

Hypernyms ("genotype" is a kind of...):

biological group (a group of plants or animals)

Hyponyms (each of the following is a kind of "genotype"):

biotype (organisms sharing a specified genotype or the genotype (or peculiarities) so shared)

Derivation:

genotypic; genotypical (of or relating to or constituting a genotype)

Sense 2

Meaning:

The particular alleles at specified loci present in an organism

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

genetic constitution; genotype

Hypernyms ("genotype" is a kind of...):

composition; constitution; make-up; makeup; physical composition (the way in which someone or something is composed)

Derivation:

genotypic; genotypical (of or relating to or constituting a genotype)

 Context examples 

An EPHX1 low-activity genotype is associated with decreased risk of lung cancer.

(EPHX1 wt Allele, NCI Thesaurus)

Any alteration in the inherited nucleic acid sequence of the genotype of an organism.

(Molecular Genetic Variation, NCI Thesaurus)

An organism with tissues derived from two or more genotypes; composed of parts that are of different origin.

(Chimera, NCI Thesaurus)

A New Zealand rabbit with black coat color and coat genotype Si, VV, E, D, C, B.

(New Zealand Black Rabbit, NCI Thesaurus/CDISC)

The production of the same or similar phenotypes (observed biochemical, physiological, and morphological characteristics of a person determined by his/her genotype) by different genetic mechanisms.

(Genetic Heterogeneity, NCI Dictionary)

A heterozygous genotype may include one normal allele and one mutation, or two different mutations.

(Heterozygosity, NCI Dictionary)

For two alleles (A and a) with frequencies p and q, there are three genotypes: AA, Aa, and aa.

(Hardy-Weinberg Distribution, NCI Thesaurus)

The research also shows the existence of ancient HBV genotypes in locations incompatible with their present-day distribution, contradicting previously-suggested geographical origins of the virus.

(Oldest genetic evidence of Hepatitis B virus found in ancient DNA from 4,500 year-old skeletons, University of Cambridge)

The GSTT1 null genotype is associated with an increased risk for the development of cancer.

(GSTT1 wt Allele, NCI Thesaurus)

The severity of the phenotype may depend on the AHSP genotype of these individuals and elevating AHSP levels through gene therapy may provide a treatment strategy for beta-thalassemia.

(Hemoglobin Chaperone Pathway, NCI Thesaurus/BIOCARTA)