GABA

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does GABA mean? 

• GABA (noun)
  The noun GABA has 1 sense:

1. an amino acid that is found in the central nervous system; acts as an inhibitory neurotransmitter

  Familiarity information: GABA used as a noun is very rare.

 Dictionary entry details 

• GABA (noun)

Sense 1

Meaning:

An amino acid that is found in the central nervous system; acts as an inhibitory neurotransmitter

Classified under:

Nouns denoting substances

Synonyms:

GABA; gamma aminobutyric acid

Hypernyms ("GABA" is a kind of...):

amino acid; aminoalkanoic acid (organic compounds containing an amino group and a carboxylic acid group)

neurotransmitter (a neurochemical that transmits nerve impulses across a synapse)

 Context examples 

This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

(Desflurane, NCI Thesaurus)

Cyclothiazide was also found to inhibit gamma-aminobutyric acid (GABA)-A receptors.

(Cyclothiazide, NCI Thesaurus)

This results in a decrease in intracellular cAMP and leads to a reduction in the release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline.

(Codeine Sulfate, NCI Thesaurus)

The agent interacts with various neurotransmitter-operated ion channels, thereby enhancing gamma-aminobutyric acid (GABA)-A receptor mediated chloride currents and inhibiting amino acid receptor-activated ion currents.

(Chloral Hydrate, NCI Thesaurus)

This, in turn, inhibits the release of various nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, noradrenaline, vasopressin, and somatostatin.

(Dextropropoxyphene Hydrochloride, NCI Thesaurus)

This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA in the CNS.

(Midazolam, NCI Thesaurus)

Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A receptor, thereby mimicking the inhibitory actions of GABA in the brain.

(Phenobarbital, NCI Thesaurus)

Subsequently, the release of nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, and noradrenaline, is inhibited.

(Oxycodone, NCI Thesaurus)

Although the mechanism of action has not been fully elucidated, oxazepam appears to enhance gamma-aminobutyric acid (GABA) receptor affinity for GABA, thereby prolonging synaptic actions of GABA.

(Oxazepam, NCI Thesaurus)

Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS).

(Brotizolam, NCI Thesaurus)