ETANERCEPT

Pronunciation (US):

(GB):

 Dictionary entry overview: What does etanercept mean? 

• ETANERCEPT (noun)
  The noun ETANERCEPT has 1 sense:

1. a genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis

  Familiarity information: ETANERCEPT used as a noun is very rare.

 Dictionary entry details 

• ETANERCEPT (noun)

Sense 1

Meaning:

A genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis

Classified under:

Nouns denoting man-made objects

Synonyms:

Enbrel; etanercept

Hypernyms ("etanercept" is a kind of...):

anti-TNF compound (a class of drugs that block the action of tumor necrosis factor (TNF); used in cases of rheumatoid arthritis because TNF instigates inflammation of the joints)

 Context examples 

While drugs such as etanercept and anakinra, which are routinely used to treat autoinflammatory and chronic diseases such as rheumatoid arthritis, had little effect on the patients, one biological drug called tocilizumab did.

(Researchers discover new autoinflammatory disease and uncover its biological cause, National Institutes of Health)

The receptor moiety of etanercept binds to circulating TNF (2 molecules of TNF per receptor) and inhibits its attachment to endogenous TNF cell surface receptors, thereby rendering TNF inactive and inhibiting TNF-mediated mechanisms of inflammation.

(Etanercept, NCI Thesaurus)