DEGRADED

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does degraded mean? 

• DEGRADED (adjective)
  The adjective DEGRADED has 2 senses:

1. unrestrained by convention or morality

2. lowered in value

  Familiarity information: DEGRADED used as an adjective is rare.

 Dictionary entry details 

• DEGRADED (adjective)

Sense 1

Meaning:

Unrestrained by convention or morality

Synonyms:

debauched; degenerate; degraded; dissipated; dissolute; fast; libertine; profligate; riotous

Context example:

fast women

Similar:

immoral (deliberately violating accepted principles of right and wrong)

Sense 2

Meaning:

Lowered in value

Synonyms:

debased; degraded; devalued

Context example:

a debased currency

Similar:

low (less than normal in degree or intensity or amount)

 Context examples 

Scientists have long believed that relatively little of the latter, called "refractory carbon," is degraded in the ocean.

(Microbes in underground aquifers beneath deep-sea Mid-Atlantic Ridge 'chow down' on carbon, National Science Foundation)

Cortactin is degraded during apoptosis in a caspase-dependent manner.

(Cortactin, NCI Thesaurus)

HIF-1 is ubiquitinated and subsequently degraded in less than 5 minutes under normoxic conditions.

(Hypoxia-Inducible Factor Pathway, NCI Thesaurus/BIOCARTA)

Following ligand binding by the heterodimer the receptors and proteins in the basal transcription machinery (like TBP and TAF135) are degraded by the proteasome.

(Chromatin Remodeling Complex and Coactivator Pathway, NCI Thesaurus/BIOCARTA)

Amilomer, a product produced by partially hydrolyzing starch and epichlorohydrin, contains degradable starch microspheres (DSM) with a diameter size of 45 micrometers that are readily degraded by amylase.

(Amilomer, NCI Thesaurus)

Mrs. John Dashwood now installed herself mistress of Norland; and her mother and sisters-in-law were degraded to the condition of visitors.

(Sense and Sensibility, by Jane Austen)

A Catabolic Process consists of activities of biologic molecules, biologic complexes, or subcellular components involved in the enzyme-catalyzed biochemical process by which complex molecules are degraded to simpler molecules releasing energy.

(Catabolic Process, NCI Thesaurus)

Catabolism is an enzyme-catalyzed biochemical process in which complex molecules are degraded to simpler molecules releasing energy.

(Catabolism, NCI Thesaurus)

By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored.

(MDM2 Antagonist RO5503781, NCI Thesaurus)

Non-coding, intervening sequences of DNA that are transcribed, but are removed from within the primary gene transcript and rapidly degraded during maturation of messenger RNA.

(Intron, NCI Thesaurus)