CROHN'S DISEASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does Crohn's disease mean? 

• CROHN'S DISEASE (noun)
  The noun CROHN'S DISEASE has 1 sense:

1. a serious chronic and progressive inflammation of the ileum producing frequent bouts of diarrhea with abdominal pain and nausea and fever and weight loss

  Familiarity information: CROHN'S DISEASE used as a noun is very rare.

 Dictionary entry details 

• CROHN'S DISEASE (noun)

Sense 1

Meaning:

A serious chronic and progressive inflammation of the ileum producing frequent bouts of diarrhea with abdominal pain and nausea and fever and weight loss

Classified under:

Nouns denoting stable states of affairs

Synonyms:

Crohn's disease; regional enteritis; regional ileitis

Hypernyms ("Crohn's disease" is a kind of...):

colitis; inflammatory bowel disease (inflammation of the colon)

 Context examples 

F. prausnitzii is a major commensal microbe in the human digestive tract and may be useful as a probiotic in individuals with Crohn's disease, but can become pathogenic in other regions.

(Faecalibacterium prausnitzii, NCI Thesaurus)

Up-regulation of the IL12RB2 gene is associated with certain infectious diseases such as Crohn's disease and leprosy.

(IL12RB2 wt Allele, NCI Thesaurus)

And the nascent development of treatments for microbiota-linked maladies operates under the idea that imbalances or deviations in the microbiome are the source of health problems, such as indigestion or Crohn's disease.

(Microbes are at work in our bodies, and researchers have figured out what they're up to, National Science Foundation)

You're also more likely to get it if you have colorectal polyps, a family history of colorectal cancer, ulcerative colitis or Crohn's disease, eat a diet high in fat, or smoke.

(Colorectal Cancer, NIH: National Cancer Institute)

Other common causes of fistulas include: • Complications from surgery • Injury • Infection • Diseases, such as Crohn's disease or ulcerative colitis

(Fistulas, NIH)

It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

(Inflammatory bowel disease, NCI Thesaurus)

Intestinal cancer is rare, but eating a high-fat diet or having Crohn's disease, celiac disease, or a history of colonic polyps can increase your risk.

(Intestinal Cancer, NIH: National Cancer Institute)

The cause of Crohn's disease is unknown.

(Crohn's Disease, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)

A study led by researchers from the Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard is the first to observe the complex set of biochemical and molecular events that disrupt the microbiome and trigger immune responses during flare-ups of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.

(New findings reveal how microbiome is disrupted during disease flare-ups, National Science Foundation)

There are many possible causes of GI bleeding, including hemorrhoids, peptic ulcers, tears or inflammation in the esophagus, diverticulosis and diverticulitis, ulcerative colitis and Crohn's disease, colonic polyps, or cancer in the colon, stomach or esophagus.

(Gastrointestinal Bleeding, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)