English Dictionary

COX

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IPA (US): 

 Dictionary entry overview: What does Cox mean? 

COX (noun)
  The noun COX has 2 senses:

1. either of two related enzymes that control the production of prostaglandins and are blocked by aspirinplay

2. the helmsman of a ship's boat or a racing crewplay

  Familiarity information: COX used as a noun is rare.


COX (verb)
  The verb COX has 1 sense:

1. act as the coxswain, in a boat raceplay

  Familiarity information: COX used as a verb is very rare.


 Dictionary entry details 


COX (noun)


Sense 1

Meaning:

Either of two related enzymes that control the production of prostaglandins and are blocked by aspirin

Classified under:

Nouns denoting substances

Synonyms:

Cox; cyclooxygenase

Hypernyms ("Cox" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "Cox"):

Cox-1; cyclooxygenase-1 (an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys)

Cox-2; cyclooxygenase-2 (an enzyme that makes prostaglandins that cause inflammation and pain and fever)


Sense 2

Meaning:

The helmsman of a ship's boat or a racing crew

Classified under:

Nouns denoting people

Synonyms:

cox; coxswain

Hypernyms ("cox" is a kind of...):

helmsman; steerer; steersman (the person who steers a ship)

Derivation:

cox (act as the coxswain, in a boat race)


COX (verb)


Sense 1

Meaning:

Act as the coxswain, in a boat race

Classified under:

Verbs of political and social activities and events

Hypernyms (to "cox" is one way to...):

be; follow (work in a specific place, with a specific subject, or in a specific function)

Sentence frame:

Somebody ----s

Derivation:

cox (the helmsman of a ship's boat or a racing crew)


 Context examples 


You and Miss Smith, and Miss Fairfax, will be three, and the two Miss Coxes five; and for five couple there will be plenty of room.

(Emma, by Jane Austen)

Arachidonic acid is converted to the prostaglandin PGG2 by the enzyme Cox-1 in platelets, and Cox-1 is inhibited by aspirin, reducing thromboxane A2 production by platelets.

(Aspirin Inhibition of Platelet Activation Pathway, NCI Thesaurus/BIOCARTA)

Until very recently, only two Cox enzymes, Cox-1 and Cox-2, were known to be targets of NSAIDS.

(Acetaminophen Pathway, NCI Thesaurus/BIOCARTA)

PGH2 synthase actually consists of two enzyme components, a cyclooxygenase and a peroxidase, and there are more than one type of cyclooxygenase, including Cox-1 and Cox-2.

(Eicosanoid Metabolism Pathway, NCI Thesaurus/BIOCARTA)

And there will be the two Gilberts, young Cox, my father, and myself, besides Mr. Knightley.

(Emma, by Jane Austen)

NSAIDS selective for Cox-2 have been developed to avoid the development of ulcers by some non-selective NSAIDs, including aspirin.

(Acetaminophen Pathway, NCI Thesaurus/BIOCARTA)

Recent NSAIDS acting selectively as Cox-2 inhibitors like Vioxx are widely used for the treatment of arthritis and other inflammatory conditions, inhibiting the production of downstream thromboxanes and prostaglandins.

(Eicosanoid Metabolism Pathway, NCI Thesaurus/BIOCARTA)

Thromboxane is a potent vasoconstrictor and platelet activator, so inhibition of Cox-1 in platelets by aspirin may explain some of the cardioprotective actions of aspirin.

(Aspirin Inhibition of Platelet Activation Pathway, NCI Thesaurus/BIOCARTA)

“You and Miss Smith, and Miss Fairfax, will be three, and the two Miss Coxes five,” had been repeated many times over.

(Emma, by Jane Austen)

Cox-2 is an inducible enzyme whose expression is induced by inflammation.

(Acetaminophen Pathway, NCI Thesaurus/BIOCARTA)



 Learn English with... Proverbs 
"It takes two to make a quarrel." (English proverb)

"He who would do great things should not attempt them all alone." (Native American proverb, Seneca)

"People follow the ways of their kings." (Arabic proverb)

"Trust yourself and your horse." (Croatian proverb)



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