COFACTOR

Pronunciation (US):

(GB):

 Dictionary entry overview: What does cofactor mean? 

• COFACTOR (noun)
  The noun COFACTOR has 1 sense:

1. a substance (as a coenzyme) that must join with another to produce a given result

  Familiarity information: COFACTOR used as a noun is very rare.

 Dictionary entry details 

• COFACTOR (noun)

Sense 1

Meaning:

A substance (as a coenzyme) that must join with another to produce a given result

Classified under:

Nouns denoting substances

Hypernyms ("cofactor" is a kind of...):

chemical compound; compound ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight)

 Context examples 

Selenium functions as a cofactor for antioxidant enzymes such as glutathione peroxidases and thioredoxin reductase.

(High-Selenium Baker's Yeast, NCI Thesaurus)

Selenium functions as a cofactor for antioxidant enzymes such as glutathione peroxidases and thioredoxin reductase, which protect cells from the free radical damage.

(high-selenium Brassica juncea, NCI Thesaurus)

Acts as a cofactor in transcriptional repression.

(HU Protein, NCI Thesaurus)

This allele, which encodes transcription cofactor HES-6 protein, is involved in the regulation of gene expression.

(HES6 wt Allele, NCI Thesaurus)

The alpha6beta4 integrin acts as a cofactor along with Meta to participate in cell growth and proliferation.

(Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta, NCI Thesaurus/BIOCARTA)

This allele, which encodes gephyrin protein, plays a role in both protein-cytoskeleton interactions and biosynthesis of the molybdenum cofactor.

(GPHN wt Allele, NCI Thesaurus)

Other nuclear RNA helicases interact with transcription factors and cofactors, suggesting that the p68 RNA helicase also may regulate interactions of transcription complexes.

(AKAP8 in Mitosis Pathway, NCI Thesaurus/BIOCARTA)

Proteins that contain a metal-containing cofactor that consists of an iron atom contained in the center of a large heterocyclic organic ring called a porphyrin.

(Heme Protein, NCI Thesaurus)

IL7 is a cofactor for V(D)J rearrangement of T cell receptor beta (TCRB) during early T cell development.

(Interleukin-7, NCI Thesaurus/LocusLink)

As a trace mineral that is toxic in high doses, selenium is a cofactor for glutathione peroxidase, an anti-oxidant enzyme that neutralizes hydrogen peroxide.

(L-Selenomethionine, NCI Thesaurus)