CHROMATID

Pronunciation (US):

(GB):

 Dictionary entry overview: What does chromatid mean? 

• CHROMATID (noun)
  The noun CHROMATID has 1 sense:

1. one of two identical strands into which a chromosome splits during mitosis

  Familiarity information: CHROMATID used as a noun is very rare.

 Dictionary entry details 

• CHROMATID (noun)

Sense 1

Meaning:

One of two identical strands into which a chromosome splits during mitosis

Classified under:

Nouns denoting body parts

Hypernyms ("chromatid" is a kind of...):

fibril; filament; strand (a very slender natural or synthetic fiber)

Holonyms ("chromatid" is a part of...):

chromosome (a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order)

 Context examples 

Sister chromatids are derived from the same chromosome.

(Chromatid, NLM, Medical Subject Headings)

In early mitosis, dramatic structural changes occur to produce metaphase chromosomes, each consisting of a pair of compacted sister chromatids (condensation).

(Mitotic Sister Chromatid Cohesion, NCI Thesaurus)

In a large number of studies, 8-Methoxypsoralen in combination with ultraviolet A radiation induced chromosomal aberrations, sister chromatid exchanges, mutation, DNA damage and DNA cross-links in human cells in vitro.

(Methoxsalen With Ultraviolet A Therapy, NCI Thesaurus)

The clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division.

(Centromere, NLM, Medical Subject Headings)

This allele, which encodes sister chromatid cohesion protein PDS5 homolog B protein, plays a role in cellular proliferation and mediates the G0/G1 cell cycle arrest in response to androgen levels.

(PDS5B wt Allele, NCI Thesaurus)

At meiosis I, homologous chromosomes recombine and then segregate to opposite poles, while the sister chromatids segregate from each other at meoisis II.

(Oocyte Meiosis Pathway, NCI Thesaurus/KEGG)

The mitotic/spindle checkpoint ensures that all replicated chromatids are properly connected to opposing spindle poles before separation (anaphase) can begin.

(Mitotic/Spindle Checkpoint, NCI Thesaurus)

KSP is an ATP-dependent microtubule motor protein that is essential for the formation of bipolar spindles and the proper segregation of sister chromatids during mitosis.

(KSP Inhibitor ARRY-520, NCI Thesaurus)

Mutation of the gene is associated with colorectal cancer, mosaic variegated aneuploidy syndrome and premature chromatid separation trait and may be involved in other carcinomas.

(BUB1B wt Allele, NCI Thesaurus)

Any substance that inhibits Aurora kinase, a serine/threonine kinase that is involved in mitotic spindle morphology, centrosome function, chromatid separation, and cytokinesis.

(Aurora Kinase Inhibitor, NCI Thesaurus)